| Lastest Insider Transactions Of RHYTHM PHARMACEUTICALS, INC. ( RYTM ) |
| Symbol | Company Name | Insider Name | Title | Date | Transation | Share | Price | Amount | File Date |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2026-08-13 | Sell | 5,079 | 119.75 | 608,210 | 2026-08-17 18:00:24 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2026-08-13 | Option Exercise | 2,024 | 6.80 | 13,763 | 2026-08-17 18:00:24 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Garfield Alastair | Chief Scientific Officer | 2026-08-13 | Sell | 7,763 | 117.57 | 912,703 | 2026-08-17 17:57:29 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Lee Jennifer Kayden | EVP, Head of North America | 2026-08-13 | Sell | 75,834 | 117.38 | 8,901,531 | 2026-08-14 19:04:44 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Lee Jennifer Kayden | EVP, Head of North America | 2026-08-13 | Option Exercise | 56,601 | 17.62 | 997,037 | 2026-08-14 19:04:44 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Mazabraud Yann | EVP, Head of International | 2026-08-12 | Sell | 57,000 | 116.15 | 6,620,575 | 2026-08-14 19:01:59 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Mazabraud Yann | EVP, Head of International | 2026-08-12 | Option Exercise | 46,625 | 6.80 | 317,050 | 2026-08-14 19:01:59 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Garfield Alastair | Chief Scientific Officer | 2026-07-01 | Option Exercise | 4,445 | 0.00 | 0 | 2026-07-02 16:52:49 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | JEAN CHRISTOPHE | Directior | 2026-06-23 | Option Exercise | 4,712 | 0.00 | 0 | 2026-06-25 18:09:37 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | MCGIRR DAVID W J | Directior | 2026-06-23 | Option Exercise | 4,712 | 0.00 | 0 | 2026-06-25 18:08:17 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | TETRAULT LYNN A. | Directior | 2026-06-23 | Option Exercise | 4,712 | 0.00 | 0 | 2026-06-25 18:06:48 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Arbuckle Stuart A | Directior | 2026-06-23 | Option Exercise | 4,712 | 0.00 | 0 | 2026-06-25 18:03:05 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | GOOD JENNIFER L | Directior | 2026-06-23 | Option Exercise | 4,712 | 0.00 | 0 | 2026-06-25 18:01:31 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | TETRAULT LYNN A. | Directior | 2026-06-22 | Sell | 37,000 | 100.32 | 3,711,896 | 2026-06-24 16:15:15 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | TETRAULT LYNN A. | Directior | 2026-06-22 | Option Exercise | 37,000 | 28.27 | 1,045,990 | 2026-06-24 16:15:15 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Smith Hunter C | Chief Financial Officer | 2026-05-18 | Option Exercise | 3,000 | 17.87 | 53,610 | 2026-05-20 16:15:19 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | German Christopher Paul | Corporate Controller & CAO | 2026-05-15 | Sell | 4,643 | 92.21 | 428,131 | 2026-05-19 16:15:19 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | German Christopher Paul | Corporate Controller & CAO | 2026-05-15 | Option Exercise | 4,442 | 42.17 | 187,313 | 2026-05-19 16:15:19 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Mazabraud Yann | EVP, Head of International | 2026-04-01 | Option Exercise | 12,875 | 0.00 | 0 | 2026-04-03 17:36:14 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | German Christopher Paul | Corporate Controller & CAO | 2026-03-04 | Sell | 5,614 | 89.56 | 502,790 | 2026-03-06 16:51:07 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | German Christopher Paul | Corporate Controller & CAO | 2026-03-04 | Option Exercise | 1,500 | 17.97 | 26,955 | 2026-03-06 16:51:07 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | German Christopher Paul | Corporate Controller & CAO | 2026-03-01 | Option Exercise | 1,162 | 0.00 | 0 | 2026-03-03 19:45:11 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Smith Hunter C | Chief Financial Officer | 2026-03-02 | Option Exercise | 6,099 | 6.80 | 41,473 | 2026-03-02 20:56:40 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Smith Hunter C | Chief Financial Officer | 2026-02-17 | Sell | 7,954 | 101.31 | 805,814 | 2026-02-19 21:02:16 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Mazabraud Yann | EVP, Head of International | 2026-02-14 | Option Exercise | 10,000 | 0.00 | 0 | 2026-02-18 16:30:22 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Smith Hunter C | Chief Financial Officer | 2026-02-10 | Sell | 7,071 | 100.21 | 708,576 | 2026-02-12 20:56:57 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Smith Hunter C | Chief Financial Officer | 2026-02-04 | Sell | 6,628 | 106.03 | 702,744 | 2026-02-06 18:38:19 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Mazabraud Yann | EVP, Head of International | 2026-02-01 | Option Exercise | 5,500 | 0.00 | 0 | 2026-02-03 16:38:11 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Smith Hunter C | Chief Financial Officer | 2026-02-01 | Option Exercise | 26,000 | 0.00 | 0 | 2026-02-03 16:36:15 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2026-02-01 | Option Exercise | 16,968 | 0.00 | 0 | 2026-02-03 16:35:20 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Lee Jennifer Kayden | EVP, Head of North America | 2026-02-01 | Option Exercise | 22,612 | 0.00 | 0 | 2026-02-03 16:33:18 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | German Christopher Paul | Corporate Controller & CAO | 2026-02-01 | Option Exercise | 3,613 | 0.00 | 0 | 2026-02-03 16:32:43 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Garfield Alastair | Chief Scientific Officer | 2026-02-01 | Option Exercise | 6,663 | 0.00 | 0 | 2026-02-03 16:31:57 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2025-12-11 | Sell | 3,350 | 111.00 | 371,850 | 2025-12-15 16:30:16 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2025-12-11 | Option Exercise | 3,350 | 27.35 | 91,623 | 2025-12-15 16:30:16 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2025-11-20 | Sell | 3,350 | 105.00 | 351,750 | 2025-11-24 16:15:18 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2025-11-20 | Option Exercise | 3,350 | 27.35 | 91,623 | 2025-11-24 16:15:18 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2025-11-07 | Sell | 22,866 | 99.00 | 2,263,826 | 2025-11-12 16:30:12 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2025-11-07 | Option Exercise | 22,866 | 11.51 | 263,086 | 2025-11-12 16:30:12 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2025-10-30 | Sell | 9,748 | 115.24 | 1,123,398 | 2025-11-03 16:30:15 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2025-10-30 | Option Exercise | 9,748 | 30.66 | 298,874 | 2025-11-03 16:30:15 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2025-10-28 | Sell | 2,815 | 115.01 | 323,750 | 2025-10-30 16:44:59 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2025-10-28 | Option Exercise | 2,815 | 28.20 | 79,377 | 2025-10-30 16:44:59 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2025-09-02 | Sell | 16,781 | 105.30 | 1,767,006 | 2025-09-04 16:30:21 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2025-09-02 | Option Exercise | 16,781 | 30.25 | 507,574 | 2025-09-04 16:30:21 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2025-08-21 | Sell | 4,188 | 100.07 | 419,091 | 2025-08-25 20:59:06 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2025-08-21 | Option Exercise | 4,188 | 27.35 | 114,542 | 2025-08-25 20:59:06 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Smith Hunter C | Chief Financial Officer | 2025-08-12 | Sell | 28,088 | 96.29 | 2,704,624 | 2025-08-14 18:48:32 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Smith Hunter C | Chief Financial Officer | 2025-08-12 | Option Exercise | 28,088 | 6.88 | 193,245 | 2025-08-14 18:48:32 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | German Christopher Paul | Corporate Controller & CAO | 2025-08-12 | Sell | 1,500 | 95.00 | 142,500 | 2025-08-14 18:47:35 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | German Christopher Paul | Corporate Controller & CAO | 2025-08-12 | Option Exercise | 1,500 | 28.39 | 42,585 | 2025-08-14 18:47:35 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2025-08-11 | Sell | 3,984 | 90.08 | 358,891 | 2025-08-13 18:32:58 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2025-08-11 | Option Exercise | 3,984 | 6.80 | 27,091 | 2025-08-13 18:32:58 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2025-07-26 | Sell | 1,520 | 85.93 | 130,614 | 2025-07-29 18:56:28 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2025-07-26 | Option Exercise | 3,125 | 0.00 | 0 | 2025-07-29 18:56:28 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2025-07-26 | Sell | 1,520 | 85.93 | 130,614 | 2025-07-29 18:56:28 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2025-07-26 | Option Exercise | 3,125 | 0.00 | 0 | 2025-07-29 18:56:28 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Smith Hunter C | Chief Financial Officer | 2025-07-09 | Sell | 42,120 | 80.48 | 3,389,756 | 2025-07-11 16:31:09 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Smith Hunter C | Chief Financial Officer | 2025-07-09 | Option Exercise | 42,120 | 6.88 | 289,786 | 2025-07-11 16:31:09 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2025-07-09 | Sell | 7,969 | 77.78 | 619,851 | 2025-07-11 16:30:51 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2025-07-09 | Option Exercise | 7,969 | 6.80 | 54,189 | 2025-07-11 16:30:51 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | German Christopher Paul | Corporate Controller & CAO | 2025-07-09 | Sell | 3,817 | 80.75 | 308,217 | 2025-07-11 16:30:31 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | German Christopher Paul | Corporate Controller & CAO | 2025-07-09 | Option Exercise | 2,850 | 27.29 | 77,786 | 2025-07-11 16:30:31 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2025-07-09 | Sell | 15,572 | 77.13 | 1,201,062 | 2025-07-11 16:30:11 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2025-07-09 | Option Exercise | 15,572 | 13.43 | 209,153 | 2025-07-11 16:30:11 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Smith Hunter C | Chief Financial Officer | 2025-07-07 | Option Exercise | 6,986 | 6.88 | 48,064 | 2025-07-08 16:30:14 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Garfield Alastair | Chief Scientific Officer | 2025-07-01 | Sell | 1,319 | 64.81 | 85,483 | 2025-07-03 17:12:03 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Garfield Alastair | Chief Scientific Officer | 2025-07-01 | Option Exercise | 4,445 | 0.00 | 0 | 2025-07-03 17:12:03 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Mathers Edward T | Directior | 2025-06-18 | Option Exercise | 4,000 | 0.00 | 0 | 2025-06-23 16:57:17 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | JEAN CHRISTOPHE | Directior | 2025-06-18 | Option Exercise | 4,000 | 0.00 | 0 | 2025-06-23 16:53:43 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | GOOD JENNIFER L | Directior | 2025-06-18 | Option Exercise | 4,000 | 0.00 | 0 | 2025-06-23 16:53:03 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Bedrosian Camille L | Directior | 2025-06-18 | Option Exercise | 4,000 | 0.00 | 0 | 2025-06-23 16:52:05 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Arbuckle Stuart A | Directior | 2025-06-18 | Option Exercise | 4,000 | 0.00 | 0 | 2025-06-23 16:51:08 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | MCGIRR DAVID W J | Directior | 2025-06-18 | Option Exercise | 4,000 | 0.00 | 0 | 2025-06-23 16:49:41 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | TETRAULT LYNN A. | Directior | 2025-06-18 | Option Exercise | 4,000 | 0.00 | 0 | 2025-06-23 16:48:06 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | German Christopher Paul | Corporate Controller & CAO | 2025-06-10 | Sell | 2,069 | 67.19 | 139,016 | 2025-06-12 16:50:02 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | German Christopher Paul | Corporate Controller & CAO | 2025-06-10 | Option Exercise | 1,069 | 17.97 | 19,210 | 2025-06-12 16:50:02 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2025-06-06 | Sell | 7,031 | 68.05 | 478,435 | 2025-06-10 16:45:22 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2025-06-06 | Option Exercise | 7,031 | 6.80 | 47,811 | 2025-06-10 16:45:22 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | MCGIRR DAVID W J | Directior | 2025-06-03 | Sell | 65,431 | 65.22 | 4,267,494 | 2025-06-05 16:16:42 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | MCGIRR DAVID W J | Directior | 2025-06-03 | Option Exercise | 65,431 | 4.59 | 300,328 | 2025-06-05 16:16:42 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Meeker David P | President and CEO | 2025-06-03 | Sell | 43,620 | 65.05 | 2,837,333 | 2025-06-05 16:16:07 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Meeker David P | President and CEO | 2025-06-03 | Option Exercise | 43,620 | 4.59 | 200,216 | 2025-06-05 16:16:07 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2025-04-29 | Sell | 7,031 | 65.09 | 457,663 | 2025-05-01 16:53:44 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2025-04-29 | Option Exercise | 7,031 | 6.80 | 47,811 | 2025-05-01 16:53:44 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Mazabraud Yann | EVP, Head of International | 2025-04-29 | Sell | 6,745 | 65.08 | 438,946 | 2025-05-01 16:52:53 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Mazabraud Yann | EVP, Head of International | 2025-04-14 | Option Exercise | 21,780 | 0.00 | 0 | 2025-04-16 16:30:22 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2025-04-08 | Sell | 20,760 | 60.14 | 1,248,490 | 2025-04-10 17:17:41 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2025-04-08 | Option Exercise | 20,760 | 13.43 | 278,853 | 2025-04-10 17:17:41 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Mazabraud Yann | EVP, Head of International | 2025-04-08 | Sell | 17,750 | 60.99 | 1,082,497 | 2025-04-10 17:16:59 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | German Christopher Paul | Corporate Controller & CAO | 2025-03-20 | Sell | 344 | 54.23 | 18,655 | 2025-03-24 17:47:56 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | German Christopher Paul | Corporate Controller & CAO | 2025-03-20 | Option Exercise | 1,163 | 0.00 | 0 | 2025-03-24 17:47:56 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Mazabraud Yann | EVP, Head of International | 2025-03-14 | Sell | 75,000 | 51.48 | 3,861,272 | 2025-03-18 21:16:52 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Mazabraud Yann | EVP, Head of International | 2025-03-14 | Option Exercise | 75,000 | 22.28 | 1,671,000 | 2025-03-18 21:16:52 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Smith Hunter C | Chief Financial Officer | 2025-02-14 | Sell | 2,215 | 57.22 | 126,742 | 2025-02-19 21:50:18 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Smith Hunter C | Chief Financial Officer | 2025-02-14 | Option Exercise | 6,600 | 0.00 | 0 | 2025-02-19 21:50:18 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2025-02-14 | Sell | 1,228 | 57.22 | 70,266 | 2025-02-19 21:49:03 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2025-02-14 | Option Exercise | 4,125 | 0.00 | 0 | 2025-02-19 21:49:03 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Meeker David P | President and CEO | 2025-02-14 | Sell | 9,896 | 57.22 | 566,249 | 2025-02-19 21:48:18 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Meeker David P | President and CEO | 2025-02-14 | Option Exercise | 21,250 | 0.00 | 0 | 2025-02-19 21:48:18 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Mazabraud Yann | EVP, Head of International | 2025-02-14 | Option Exercise | 5,500 | 0.00 | 0 | 2025-02-19 21:47:19 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Lee Jennifer Kayden | EVP, Head of North America | 2025-02-14 | Sell | 2,035 | 57.22 | 116,443 | 2025-02-19 21:46:08 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Lee Jennifer Kayden | EVP, Head of North America | 2025-02-14 | Option Exercise | 5,500 | 0.00 | 0 | 2025-02-19 21:46:08 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | German Christopher Paul | Corporate Controller & CAO | 2025-02-14 | Sell | 635 | 57.22 | 36,335 | 2025-02-19 21:45:16 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | German Christopher Paul | Corporate Controller & CAO | 2025-02-14 | Option Exercise | 1,807 | 0.00 | 0 | 2025-02-19 21:45:16 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2025-02-14 | Sell | 982 | 57.22 | 56,190 | 2025-02-19 21:43:10 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2025-02-14 | Option Exercise | 3,300 | 0.00 | 0 | 2025-02-19 21:43:10 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Smith Hunter C | Chief Financial Officer | 2025-02-12 | Sell | 751 | 56.39 | 42,347 | 2025-02-14 16:59:13 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2025-02-12 | Sell | 469 | 56.40 | 26,452 | 2025-02-14 16:57:22 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Lee Jennifer Kayden | EVP, Head of North America | 2025-02-12 | Sell | 3,020 | 57.03 | 172,238 | 2025-02-14 16:55:57 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2025-02-09 | Sell | 794 | 57.51 | 45,663 | 2025-02-11 21:47:07 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2025-02-09 | Option Exercise | 4,218 | 0.00 | 0 | 2025-02-11 21:47:07 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Lee Jennifer Kayden | EVP, Head of North America | 2025-02-09 | Sell | 5,216 | 58.64 | 305,846 | 2025-02-11 21:46:12 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Lee Jennifer Kayden | EVP, Head of North America | 2025-02-09 | Option Exercise | 9,657 | 2.95 | 28,485 | 2025-02-11 21:46:12 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Lee Jennifer Kayden | EVP, Head of North America | 2025-02-09 | Sell | 5,216 | 58.64 | 305,846 | 2025-02-11 21:46:12 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Lee Jennifer Kayden | EVP, Head of North America | 2025-02-09 | Option Exercise | 9,657 | 2.95 | 28,485 | 2025-02-11 21:46:12 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2025-02-09 | Sell | 701 | 57.51 | 40,315 | 2025-02-11 21:45:13 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2025-02-09 | Option Exercise | 2,344 | 0.00 | 0 | 2025-02-11 21:45:13 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2025-02-09 | Sell | 701 | 57.51 | 40,315 | 2025-02-11 21:45:13 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2025-02-09 | Option Exercise | 2,344 | 0.00 | 0 | 2025-02-11 21:45:13 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Smith Hunter C | Chief Financial Officer | 2025-02-09 | Sell | 1,296 | 57.51 | 74,533 | 2025-02-11 21:44:16 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Smith Hunter C | Chief Financial Officer | 2025-02-09 | Option Exercise | 6,405 | 0.00 | 0 | 2025-02-11 21:44:16 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Lee Jennifer Kayden | EVP, Head of North America | 2025-02-05 | Sell | 3,066 | 60.55 | 185,640 | 2025-02-07 17:05:53 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Smith Hunter C | Chief Financial Officer | 2025-02-01 | Sell | 1,678 | 59.43 | 99,724 | 2025-02-04 21:27:41 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Smith Hunter C | Chief Financial Officer | 2025-02-01 | Option Exercise | 4,925 | 0.00 | 0 | 2025-02-04 21:27:41 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2025-02-01 | Sell | 1,281 | 59.43 | 76,130 | 2025-02-04 21:26:23 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2025-02-01 | Option Exercise | 3,938 | 0.00 | 0 | 2025-02-04 21:26:23 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Meeker David P | President and CEO | 2025-02-01 | Sell | 4,278 | 59.43 | 254,242 | 2025-02-04 21:25:31 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Meeker David P | President and CEO | 2025-02-01 | Option Exercise | 14,125 | 0.00 | 0 | 2025-02-04 21:25:31 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Lee Jennifer Kayden | EVP, Head of North America | 2025-02-01 | Sell | 1,447 | 59.43 | 85,995 | 2025-02-04 21:23:52 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Lee Jennifer Kayden | EVP, Head of North America | 2025-02-01 | Option Exercise | 4,513 | 0.00 | 0 | 2025-02-04 21:23:52 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2025-02-01 | Sell | 902 | 59.43 | 53,606 | 2025-02-04 21:22:17 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2025-02-01 | Option Exercise | 2,650 | 0.00 | 0 | 2025-02-04 21:22:17 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Lee Jennifer Kayden | EVP, Head of North America | 2024-11-11 | Sell | 66,861 | 66.33 | 4,434,883 | 2024-11-13 21:04:32 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Lee Jennifer Kayden | EVP, Head of North America | 2024-11-11 | Option Exercise | 60,981 | 19.59 | 1,194,709 | 2024-11-13 21:04:32 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2024-11-11 | Sell | 13,281 | 66.44 | 882,341 | 2024-11-13 21:02:57 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2024-11-11 | Option Exercise | 13,281 | 12.63 | 167,760 | 2024-11-13 21:02:57 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2024-02-09 | Option Exercise | 69,160 | 20.54 | 1,420,540 | 2024-11-13 21:01:54 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2024-11-06 | Sell | 9,375 | 62.50 | 585,940 | 2024-11-08 16:15:05 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2024-11-06 | Option Exercise | 9,375 | 19.02 | 178,313 | 2024-11-08 16:15:05 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | GOOD JENNIFER L | Directior | 2024-09-17 | Sell | 31,751 | 52.40 | 1,663,803 | 2024-09-19 16:30:09 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | GOOD JENNIFER L | Directior | 2024-09-17 | Option Exercise | 31,751 | 21.54 | 684,067 | 2024-09-19 16:30:09 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | GOOD JENNIFER L | Directior | 2024-08-26 | Sell | 14,508 | 50.01 | 725,526 | 2024-08-28 16:30:13 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | GOOD JENNIFER L | Directior | 2024-08-26 | Option Exercise | 14,508 | 18.63 | 270,322 | 2024-08-28 16:30:13 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | TETRAULT LYNN A. | Directior | 2024-08-12 | Sell | 10,000 | 44.65 | 446,462 | 2024-08-14 16:15:12 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | TETRAULT LYNN A. | Directior | 2024-08-12 | Option Exercise | 10,000 | 4.15 | 41,500 | 2024-08-14 16:15:12 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2024-08-09 | Sell | 49,006 | 45.15 | 2,212,498 | 2024-08-13 16:45:20 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2024-08-09 | Option Exercise | 30,771 | 19.02 | 585,264 | 2024-08-13 16:45:20 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2024-07-26 | Sell | 1,395 | 49.06 | 68,439 | 2024-07-30 17:09:23 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2024-07-26 | Option Exercise | 3,125 | 0.00 | 0 | 2024-07-30 17:09:23 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2024-07-16 | Sell | 10,468 | 53.00 | 554,817 | 2024-07-18 17:59:08 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2024-07-16 | Option Exercise | 10,468 | 27.35 | 286,300 | 2024-07-18 17:59:08 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2024-07-12 | Sell | 5,313 | 50.01 | 265,725 | 2024-07-16 16:30:34 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2024-07-12 | Option Exercise | 5,313 | 21.38 | 113,592 | 2024-07-16 16:30:34 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Arbuckle Stuart A | Directior | 2024-06-21 | Option Exercise | 3,000 | 0.00 | 0 | 2024-06-25 16:41:15 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | MCGIRR DAVID W J | Directior | 2024-06-21 | Option Exercise | 3,000 | 0.00 | 0 | 2024-06-25 16:39:45 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | TETRAULT LYNN A. | Directior | 2024-06-21 | Option Exercise | 3,000 | 0.00 | 0 | 2024-06-25 16:38:44 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Mathers Edward T | Directior | 2024-06-21 | Option Exercise | 3,000 | 0.00 | 0 | 2024-06-25 16:38:22 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Bedrosian Camille L | Directior | 2024-06-21 | Option Exercise | 3,000 | 0.00 | 0 | 2024-06-25 16:37:07 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | JEAN CHRISTOPHE | Directior | 2024-06-21 | Option Exercise | 3,000 | 0.00 | 0 | 2024-06-25 16:35:08 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | GOOD JENNIFER L | Directior | 2024-06-21 | Option Exercise | 3,000 | 0.00 | 0 | 2024-06-25 16:30:21 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2024-05-09 | Sell | 3,984 | 38.47 | 153,259 | 2024-05-13 16:21:39 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2024-05-09 | Option Exercise | 3,984 | 6.80 | 27,091 | 2024-05-13 16:21:39 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Mazabraud Yann | EVP, Head of International | 2024-04-14 | Option Exercise | 10,375 | 0.00 | 0 | 2024-04-16 20:11:12 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | German Christopher Paul | Corporate Controller & CAO | 2024-03-20 | Sell | 368 | 41.76 | 15,368 | 2024-04-03 20:00:51 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | German Christopher Paul | Corporate Controller & CAO | 2024-03-20 | Option Exercise | 1,163 | 0.00 | 0 | 2024-04-03 20:00:51 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2024-03-21 | Sell | 18,235 | 40.34 | 735,600 | 2024-03-22 16:55:19 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Lee Jennifer Kayden | EVP, Head of North America | 2024-03-20 | Sell | 18,235 | 38.77 | 707,005 | 2024-03-22 16:16:08 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Smith Hunter C | Chief Financial Officer | 2024-03-19 | Sell | 15,515 | 39.22 | 608,498 | 2024-03-19 20:57:43 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2024-03-19 | Sell | 15,515 | 39.22 | 608,498 | 2024-03-19 20:56:21 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Meeker David P | President and CEO | 2024-03-19 | Sell | 45,494 | 39.22 | 1,784,275 | 2024-03-19 20:54:47 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Mazabraud Yann | EVP, Head of International | 2024-03-19 | Sell | 16,000 | 39.22 | 627,520 | 2024-03-19 20:53:34 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Lee Jennifer Kayden | EVP, Head of North America | 2024-03-19 | Sell | 15,515 | 39.22 | 608,498 | 2024-03-19 20:52:17 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2024-03-19 | Sell | 15,515 | 39.22 | 608,498 | 2024-03-19 20:50:30 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2024-02-13 | Sell | 2,954 | 50.00 | 147,711 | 2024-02-15 18:14:25 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Smith Hunter C | Chief Financial Officer | 2024-02-09 | Sell | 1,918 | 50.80 | 97,441 | 2024-02-13 20:50:20 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Smith Hunter C | Chief Financial Officer | 2024-02-09 | Option Exercise | 6,407 | 0.00 | 0 | 2024-02-13 20:50:20 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Mazabraud Yann | EVP, Head of International | 2024-02-09 | Sell | 2,551 | 50.80 | 129,597 | 2024-02-13 20:49:16 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Mazabraud Yann | EVP, Head of International | 2024-02-09 | Option Exercise | 5,469 | 0.00 | 0 | 2024-02-13 20:49:16 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Lee Jennifer Kayden | EVP, Head of North America | 2024-02-09 | Sell | 1,638 | 50.80 | 83,207 | 2024-02-13 20:47:39 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Lee Jennifer Kayden | EVP, Head of North America | 2024-02-09 | Option Exercise | 5,469 | 0.00 | 0 | 2024-02-13 20:47:39 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2024-02-09 | Sell | 73,038 | 50.39 | 3,680,198 | 2024-02-13 20:46:14 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2024-02-09 | Option Exercise | 73,408 | 20.15 | 1,479,282 | 2024-02-13 20:46:14 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2024-02-09 | Sell | 696 | 51.38 | 35,760 | 2024-02-13 20:45:18 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2024-02-09 | Option Exercise | 2,344 | 0.00 | 0 | 2024-02-13 20:45:18 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Lee Jennifer Kayden | EVP, Head of North America | 2024-02-01 | Sell | 1,492 | 45.06 | 67,230 | 2024-02-05 18:55:36 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Lee Jennifer Kayden | EVP, Head of North America | 2024-02-01 | Option Exercise | 4,513 | 0.00 | 0 | 2024-02-05 18:55:36 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Smith Hunter C | Chief Financial Officer | 2024-02-01 | Sell | 1,616 | 45.06 | 72,817 | 2024-02-05 18:54:38 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Smith Hunter C | Chief Financial Officer | 2024-02-01 | Option Exercise | 4,925 | 0.00 | 0 | 2024-02-05 18:54:38 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2024-02-01 | Sell | 1,324 | 45.06 | 59,659 | 2024-02-05 18:54:08 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2024-02-01 | Option Exercise | 3,938 | 0.00 | 0 | 2024-02-05 18:54:08 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Meeker David P | President and CEO | 2024-02-01 | Sell | 4,361 | 45.06 | 196,507 | 2024-02-05 18:53:36 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Meeker David P | President and CEO | 2024-02-01 | Option Exercise | 14,125 | 0.00 | 0 | 2024-02-05 18:53:36 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2024-02-01 | Sell | 946 | 45.06 | 42,627 | 2024-02-05 18:53:09 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Cramer Pamela J. | Chief Human Resources Officer | 2024-02-01 | Option Exercise | 2,650 | 0.00 | 0 | 2024-02-05 18:53:09 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2023-12-27 | Sell | 12,941 | 50.00 | 647,114 | 2023-12-29 16:30:27 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Shulman Joseph | Chief Technical Officer | 2023-12-27 | Option Exercise | 9,200 | 21.38 | 196,696 | 2023-12-29 16:30:27 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Smith Hunter C | Chief Financial Officer | 2023-12-05 | Sell | 27,026 | 38.72 | 1,046,360 | 2023-12-07 16:16:44 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Smith Hunter C | Chief Financial Officer | 2023-12-05 | Option Exercise | 27,026 | 6.88 | 185,939 | 2023-12-07 16:16:44 |
| RYTM | RHYTHM PHARMACEUTICALS, INC. | Smith Hunter C | Chief Financial Officer | 2023-11-24 | Sell | 10,974 | 35.02 | 384,336 | 2023-11-28 16:05:35 |
