| Lastest Insider Transactions Of LEXICON PHARMACEUTICALS, INC. ( LXRX ) |
| Symbol | Company Name | Insider Name | Title | Date | Transation | Share | Price | Amount | File Date |
| LXRX | LEXICON PHARMACEUTICALS, INC. | Swain Judith L | Directior | 2026-06-03 | Option Exercise | 89,312 | 0.00 | 0 | 2026-06-04 16:14:34 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | Sullivan Diane E. | Directior | 2026-06-03 | Option Exercise | 89,312 | 0.00 | 0 | 2026-06-04 16:13:55 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | SOBECKI CHRISTOPHER J | Directior | 2026-06-03 | Option Exercise | 89,312 | 0.00 | 0 | 2026-06-04 16:13:09 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | Cheung Ivan | Directior | 2026-06-03 | Option Exercise | 89,312 | 0.00 | 0 | 2026-06-04 16:12:20 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | BARKER SAM L | Directior | 2026-06-03 | Option Exercise | 89,312 | 0.00 | 0 | 2026-06-04 16:11:35 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | Amouyal Philippe | Directior | 2026-06-03 | Option Exercise | 89,312 | 0.00 | 0 | 2026-06-04 16:10:52 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | DEBBANE RAYMOND | Directior | 2026-06-03 | Option Exercise | 89,312 | 0.00 | 0 | 2026-06-04 16:09:59 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | Artal Participations S.a r.l. | Directior 10% Owner | 2026-04-30 | Option Exercise | 20,421,735 | 0.00 | 0 | 2026-05-08 21:45:20 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | McDermott Wendy | SVP, Human Resources | 2026-02-28 | Option Exercise | 224,406 | 0.00 | 0 | 2026-03-03 07:20:59 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | Martens Rachel Yap | SVP, Partnerships & Corp Strat | 2026-02-28 | Option Exercise | 67,090 | 0.00 | 0 | 2026-03-03 07:20:20 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | Granowitz Craig B | SVP, Chief Medical Officer | 2026-02-28 | Option Exercise | 312,276 | 0.00 | 0 | 2026-03-03 07:19:33 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | Gopinathan Suma | SVP, Discovery | 2026-02-28 | Option Exercise | 99,950 | 0.00 | 0 | 2026-03-03 07:18:43 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | DeFrancesco Lisa | SVP, IR and Corp Comm | 2026-02-28 | Option Exercise | 152,864 | 0.00 | 0 | 2026-03-03 07:18:00 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | Crum Brian T | SVP, General Counsel & Secr. | 2026-02-28 | Option Exercise | 273,006 | 0.00 | 0 | 2026-03-03 07:17:13 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | Coiante Scott M | SVP, Chief Financial Officer | 2026-02-28 | Option Exercise | 160,237 | 0.00 | 0 | 2026-03-03 07:16:31 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | Exton Michael | Chief Executive Officer | 2026-02-28 | Option Exercise | 503,263 | 0.00 | 0 | 2026-03-03 07:15:34 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | DEBBANE RAYMOND | Directior | 2026-02-25 | Buy | 2,000 | 1.49 | 2,980 | 2026-02-27 08:33:21 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | DEBBANE RAYMOND | Directior | 2026-02-23 | Buy | 100,000 | 1.47 | 147,000 | 2026-02-25 07:00:27 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | DEBBANE RAYMOND | Directior | 2026-02-19 | Buy | 150,000 | 1.47 | 219,755 | 2026-02-23 07:49:43 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | DEBBANE RAYMOND | Directior | 2026-02-13 | Buy | 268,497 | 1.31 | 352,889 | 2026-02-18 16:30:52 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | Invus Global Management, LLC | Directior 10% Owner | 2026-02-02 | Buy | 1,538,462 | 1.30 | 2,000,001 | 2026-02-04 16:25:05 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | Swain Judith L | Directior | 2025-05-13 | Option Exercise | 36,810 | 0.00 | 0 | 2025-05-13 17:52:13 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | Sullivan Diane E. | Directior | 2025-05-13 | Option Exercise | 36,810 | 0.00 | 0 | 2025-05-13 17:51:31 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | SOBECKI CHRISTOPHER J | Directior | 2025-05-13 | Option Exercise | 36,810 | 0.00 | 0 | 2025-05-13 17:50:50 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | BARKER SAM L | Directior | 2025-05-13 | Option Exercise | 36,810 | 0.00 | 0 | 2025-05-13 17:50:10 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | Amouyal Philippe | Directior | 2025-05-13 | Option Exercise | 36,810 | 0.00 | 0 | 2025-05-13 17:49:27 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | DEBBANE RAYMOND | Directior | 2025-05-13 | Option Exercise | 36,810 | 0.00 | 0 | 2025-05-13 17:48:38 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | Alexander Kristen | VP, Finance and Accounting | 2025-02-28 | Option Exercise | 46,430 | 0.00 | 0 | 2025-03-03 16:33:57 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | McDermott Wendy | SVP, Human Resources | 2025-02-28 | Option Exercise | 98,956 | 0.00 | 0 | 2025-03-03 16:33:08 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | MAIN ALAN J | EVP, Innov & Chem Sciences | 2025-02-28 | Option Exercise | 126,814 | 0.00 | 0 | 2025-03-03 16:32:25 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | Granowitz Craig B | SVP, Chief Medical Officer | 2025-02-28 | Option Exercise | 137,934 | 0.00 | 0 | 2025-03-03 16:31:11 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | DeFrancesco Lisa | SVP, IR and Corp Comm | 2025-02-28 | Option Exercise | 24,673 | 0.00 | 0 | 2025-03-03 16:30:24 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | Crum Brian T | SVP, General Counsel & Secr. | 2025-02-28 | Option Exercise | 128,940 | 0.00 | 0 | 2025-03-03 16:28:42 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | Artal International S.C.A. | Directior 10% Owner | 2024-05-10 | Option Exercise | 57,546,100 | 0.00 | 0 | 2024-05-14 17:17:40 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | Swain Judith L | Directior | 2024-04-28 | Option Exercise | 8,032 | 0.00 | 0 | 2024-04-29 16:21:37 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | SOBECKI CHRISTOPHER J | Directior | 2024-04-28 | Option Exercise | 8,032 | 0.00 | 0 | 2024-04-29 16:20:43 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | LEFKOWITZ ROBERT J MD | Directior | 2024-04-28 | Option Exercise | 8,032 | 0.00 | 0 | 2024-04-29 16:18:45 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | DEBBANE RAYMOND | Directior | 2024-04-28 | Option Exercise | 8,032 | 0.00 | 0 | 2024-04-29 16:17:58 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | BARKER SAM L | Directior | 2024-04-28 | Option Exercise | 8,032 | 0.00 | 0 | 2024-04-29 16:17:09 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | Amouyal Philippe | Directior | 2024-04-28 | Option Exercise | 8,032 | 0.00 | 0 | 2024-04-29 16:16:09 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | MAIN ALAN J | EVP, Innov & Chem Sciences | 2024-02-28 | Option Exercise | 67,546 | 0.00 | 0 | 2024-02-29 16:30:47 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | Kassler-Taub Kenneth B. | SVP, Regulatory & QA | 2024-02-28 | Option Exercise | 67,400 | 0.00 | 0 | 2024-02-29 16:29:48 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | Granowitz Craig B | SVP, Chief Medical Officer | 2024-02-28 | Option Exercise | 63,706 | 0.00 | 0 | 2024-02-29 16:28:56 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | COATS LONNEL | Chief Executive Officer | 2024-02-28 | Option Exercise | 245,080 | 0.00 | 0 | 2024-02-29 16:26:53 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | COATS LONNEL | Chief Executive Officer | 2023-11-16 | Buy | 90,000 | 1.05 | 94,797 | 2023-11-17 16:55:09 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | COATS LONNEL | Chief Executive Officer | 2023-11-10 | Buy | 10,000 | 1.01 | 10,100 | 2023-11-13 17:31:49 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | DEBBANE RAYMOND | Directior | 2023-10-10 | Buy | 1,000,000 | 1.10 | 1,103,957 | 2023-10-12 16:01:18 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | WADE JEFFREY L | President and CFO | 2023-09-14 | Buy | 10,000 | 1.38 | 13,800 | 2023-09-14 17:05:40 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | McDermott Wendy | VP, Human Resources | 2023-08-04 | Buy | 6,000 | 1.84 | 11,040 | 2023-08-07 16:13:16 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | COATS LONNEL | Chief Executive Officer | 2023-06-29 | Buy | 10,000 | 2.16 | 21,600 | 2023-06-29 16:13:50 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | McDermott Wendy | VP, Human Resources | 2023-06-23 | Buy | 10,000 | 2.43 | 24,300 | 2023-06-27 16:22:13 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | COATS LONNEL | Chief Executive Officer | 2023-06-23 | Buy | 20,000 | 2.34 | 46,742 | 2023-06-26 16:04:07 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | COATS LONNEL | Chief Executive Officer | 2023-06-22 | Buy | 40,000 | 2.31 | 92,400 | 2023-06-22 16:01:14 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | WADE JEFFREY L | President and CFO | 2023-06-20 | Buy | 12,000 | 2.33 | 28,000 | 2023-06-20 16:10:33 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | Artal International S.C.A. | Directior 10% Owner | 2023-06-05 | Buy | 27,775,050 | 2.60 | 72,215,128 | 2023-06-05 16:46:00 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | Swain Judith L | Directior | 2023-05-21 | Option Exercise | 9,302 | 0.00 | 0 | 2023-05-22 16:07:28 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | SOBECKI CHRISTOPHER J | Directior | 2023-05-21 | Option Exercise | 9,302 | 0.00 | 0 | 2023-05-22 16:06:47 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | Palantoni Frank | Directior | 2023-05-21 | Option Exercise | 9,302 | 0.00 | 0 | 2023-05-22 16:06:07 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | NIES ALAN S | Directior | 2023-05-21 | Option Exercise | 9,302 | 0.00 | 0 | 2023-05-22 16:05:20 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | LEFKOWITZ ROBERT J MD | Directior | 2023-05-21 | Option Exercise | 9,302 | 0.00 | 0 | 2023-05-22 16:04:39 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | DEBBANE RAYMOND | Directior | 2023-05-21 | Option Exercise | 9,302 | 0.00 | 0 | 2023-05-22 16:03:46 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | BARKER SAM L | Directior | 2023-05-21 | Option Exercise | 9,302 | 0.00 | 0 | 2023-05-22 16:02:55 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | Amouyal Philippe | Directior | 2023-05-21 | Option Exercise | 9,302 | 0.00 | 0 | 2023-05-22 16:01:46 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | Alexander Kristen | VP, Finance and Accounting | 2023-02-28 | Option Exercise | 18,717 | 0.00 | 0 | 2023-03-01 16:56:29 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | Seth Kiernan | VP, Chief Commercial Officer | 2023-02-28 | Option Exercise | 43,082 | 0.00 | 0 | 2023-03-01 16:55:29 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | McDermott Wendy | VP, Human Resources | 2023-02-28 | Option Exercise | 18,943 | 0.00 | 0 | 2023-03-01 16:54:25 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | MAIN ALAN J | EVP, Innov & Chem Sciences | 2023-02-28 | Option Exercise | 57,943 | 0.00 | 0 | 2023-03-01 16:53:02 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | Kassler-Taub Kenneth B. | SVP, Regulatory & QA | 2023-02-28 | Option Exercise | 52,886 | 0.00 | 0 | 2023-03-01 16:51:47 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | Granowitz Craig B | SVP, Chief Medical Officer | 2023-02-28 | Option Exercise | 27,917 | 0.00 | 0 | 2023-03-01 16:50:54 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | Crum Brian T | SVP, General Counsel & Secr. | 2023-02-28 | Option Exercise | 55,877 | 0.00 | 0 | 2023-03-01 16:49:51 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | Crum Brian T | SVP, General Counsel & Secr. | 2023-02-28 | Option Exercise | 55,877 | 0.00 | 0 | 2023-03-01 16:49:51 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | WADE JEFFREY L | President and CFO | 2023-02-28 | Option Exercise | 78,916 | 0.00 | 0 | 2023-03-01 16:48:08 |
| LXRX | LEXICON PHARMACEUTICALS, INC. | COATS LONNEL | Chief Executive Officer | 2023-02-28 | Option Exercise | 209,327 | 0.00 | 0 | 2023-03-01 16:46:57 |
