| Lastest Insider Transactions Of IONIS PHARMACEUTICALS INC ( IONS ) |
| Symbol | Company Name | Insider Name | Title | Date | Transation | Share | Price | Amount | File Date |
| IONS | IONIS PHARMACEUTICALS INC | Devers Shannon L. | EVP, Chief Human Resources Ofc | 2026-01-22 | Sell | 3,977 | 81.34 | 323,490 | 2026-01-23 17:51:50 |
| IONS | IONIS PHARMACEUTICALS INC | YANG MICHAEL J. | Directior | 2026-01-15 | Option Exercise | 1,930 | 0.00 | 0 | 2026-01-20 20:21:43 |
| IONS | IONIS PHARMACEUTICALS INC | Swayze Eric | EVP Research | 2026-01-15 | Sell | 9,933 | 75.34 | 748,383 | 2026-01-20 20:21:37 |
| IONS | IONIS PHARMACEUTICALS INC | Swayze Eric | EVP Research | 2026-01-15 | Option Exercise | 21,477 | 0.00 | 0 | 2026-01-20 20:21:37 |
| IONS | IONIS PHARMACEUTICALS INC | Schneider Eugene | EVP, Chf Clinical Develop Ofcr | 2026-01-15 | Sell | 9,302 | 75.59 | 703,138 | 2026-01-20 20:21:31 |
| IONS | IONIS PHARMACEUTICALS INC | Schneider Eugene | EVP, Chf Clinical Develop Ofcr | 2026-01-15 | Option Exercise | 21,685 | 0.00 | 0 | 2026-01-20 20:21:31 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2026-01-15 | Sell | 9,191 | 75.84 | 697,045 | 2026-01-20 20:20:29 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2026-01-15 | Option Exercise | 21,473 | 0.00 | 0 | 2026-01-20 20:20:29 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2026-01-15 | Sell | 44,034 | 74.82 | 3,294,624 | 2026-01-20 20:20:23 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2026-01-15 | Option Exercise | 89,145 | 0.00 | 0 | 2026-01-20 20:20:23 |
| IONS | IONIS PHARMACEUTICALS INC | Kordasiewicz Holly B. | EVP, Chief Development Officer | 2026-01-15 | Sell | 4,141 | 75.66 | 313,308 | 2026-01-20 20:18:47 |
| IONS | IONIS PHARMACEUTICALS INC | Kordasiewicz Holly B. | EVP, Chief Development Officer | 2026-01-15 | Option Exercise | 11,119 | 0.00 | 0 | 2026-01-20 20:18:47 |
| IONS | IONIS PHARMACEUTICALS INC | Jenne Kyle | EVP, Chf GL Pdt Str Ofcr | 2026-01-15 | Sell | 1,823 | 75.96 | 138,475 | 2026-01-20 20:18:39 |
| IONS | IONIS PHARMACEUTICALS INC | Jenne Kyle | EVP, Chf GL Pdt Str Ofcr | 2026-01-15 | Option Exercise | 7,013 | 0.00 | 0 | 2026-01-20 20:18:39 |
| IONS | IONIS PHARMACEUTICALS INC | HOUGEN ELIZABETH L | EVP, Finance & CFO | 2026-01-15 | Sell | 12,922 | 75.22 | 971,993 | 2026-01-20 20:18:32 |
| IONS | IONIS PHARMACEUTICALS INC | HOUGEN ELIZABETH L | EVP, Finance & CFO | 2026-01-15 | Option Exercise | 28,729 | 0.00 | 0 | 2026-01-20 20:18:32 |
| IONS | IONIS PHARMACEUTICALS INC | HOUGEN ELIZABETH L | EVP, Finance & CFO | 2026-01-15 | Sell | 12,922 | 75.22 | 971,993 | 2026-01-20 20:18:32 |
| IONS | IONIS PHARMACEUTICALS INC | HOUGEN ELIZABETH L | EVP, Finance & CFO | 2026-01-15 | Option Exercise | 28,729 | 0.00 | 0 | 2026-01-20 20:18:32 |
| IONS | IONIS PHARMACEUTICALS INC | Devers Shannon L. | EVP, Chief Human Resources Ofc | 2026-01-15 | Sell | 8,353 | 75.95 | 634,410 | 2026-01-20 20:18:26 |
| IONS | IONIS PHARMACEUTICALS INC | Devers Shannon L. | EVP, Chief Human Resources Ofc | 2026-01-15 | Option Exercise | 17,377 | 0.00 | 0 | 2026-01-20 20:18:26 |
| IONS | IONIS PHARMACEUTICALS INC | Birchler Brian | EVP, Corp and Development Ops | 2026-01-15 | Sell | 8,480 | 75.11 | 636,933 | 2026-01-20 20:18:16 |
| IONS | IONIS PHARMACEUTICALS INC | Birchler Brian | EVP, Corp and Development Ops | 2026-01-15 | Option Exercise | 20,089 | 0.00 | 0 | 2026-01-20 20:18:16 |
| IONS | IONIS PHARMACEUTICALS INC | BENNETT C FRANK | EVP, Chief Scientific Officer | 2026-01-15 | Sell | 8,977 | 75.15 | 674,622 | 2026-01-20 20:18:10 |
| IONS | IONIS PHARMACEUTICALS INC | BENNETT C FRANK | EVP, Chief Scientific Officer | 2026-01-15 | Option Exercise | 21,055 | 0.00 | 0 | 2026-01-20 20:18:10 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2026-01-15 | Sell | 8,056 | 75.75 | 610,277 | 2026-01-20 20:18:04 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2026-01-15 | Option Exercise | 19,887 | 0.00 | 0 | 2026-01-20 20:18:04 |
| IONS | IONIS PHARMACEUTICALS INC | Devers Shannon L. | EVP, Chief Human Resources Ofc | 2026-01-07 | Sell | 44,199 | 85.08 | 3,760,578 | 2026-01-09 17:08:28 |
| IONS | IONIS PHARMACEUTICALS INC | Devers Shannon L. | EVP, Chief Human Resources Ofc | 2026-01-07 | Option Exercise | 44,199 | 51.25 | 2,265,415 | 2026-01-09 17:08:28 |
| IONS | IONIS PHARMACEUTICALS INC | Swayze Eric | EVP Research | 2026-01-02 | Sell | 23,463 | 79.12 | 1,856,325 | 2026-01-06 17:35:26 |
| IONS | IONIS PHARMACEUTICALS INC | Swayze Eric | EVP Research | 2026-01-02 | Option Exercise | 23,463 | 60.89 | 1,428,662 | 2026-01-06 17:35:26 |
| IONS | IONIS PHARMACEUTICALS INC | WENDER JOSEPH H | Directior | 2025-12-01 | Sell | 28,000 | 80.82 | 2,262,848 | 2025-12-03 19:01:07 |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Directior | 2025-11-25 | Sell | 12,000 | 80.00 | 960,000 | 2025-11-28 17:51:58 |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Directior | 2025-11-25 | Option Exercise | 12,000 | 0.00 | 0 | 2025-11-28 17:51:58 |
| IONS | IONIS PHARMACEUTICALS INC | Devers Shannon L. | EVP, Chief Human Resources Ofc | 2025-11-25 | Sell | 16,777 | 80.91 | 1,357,442 | 2025-11-28 17:51:52 |
| IONS | IONIS PHARMACEUTICALS INC | Devers Shannon L. | EVP, Chief Human Resources Ofc | 2025-11-25 | Option Exercise | 16,777 | 53.77 | 902,099 | 2025-11-28 17:51:52 |
| IONS | IONIS PHARMACEUTICALS INC | Devers Shannon L. | EVP, Chief Human Resources Ofc | 2025-11-25 | Sell | 16,777 | 80.91 | 1,357,442 | 2025-11-28 17:51:52 |
| IONS | IONIS PHARMACEUTICALS INC | Devers Shannon L. | EVP, Chief Human Resources Ofc | 2025-11-25 | Option Exercise | 16,777 | 53.77 | 902,099 | 2025-11-28 17:51:52 |
| IONS | IONIS PHARMACEUTICALS INC | WENDER JOSEPH H | Directior | 2025-11-18 | Option Exercise | 16,000 | 24.42 | 390,720 | 2025-11-20 17:12:23 |
| IONS | IONIS PHARMACEUTICALS INC | HERMAN JOAN E | Directior | 2025-11-19 | Sell | 44,000 | 72.13 | 3,173,830 | 2025-11-20 17:12:11 |
| IONS | IONIS PHARMACEUTICALS INC | HERMAN JOAN E | Directior | 2025-11-19 | Option Exercise | 44,000 | 57.40 | 2,525,400 | 2025-11-20 17:12:11 |
| IONS | IONIS PHARMACEUTICALS INC | Birchler Brian | EVP, Corp and Development Ops | 2025-11-06 | Sell | 8,000 | 76.17 | 609,379 | 2025-11-07 17:13:09 |
| IONS | IONIS PHARMACEUTICALS INC | Geary Richard S | EVP, Chief Development Officer | 2025-11-05 | Sell | 34,639 | 75.69 | 2,621,816 | 2025-11-07 17:12:44 |
| IONS | IONIS PHARMACEUTICALS INC | Geary Richard S | EVP, Chief Development Officer | 2025-11-05 | Option Exercise | 34,639 | 59.05 | 2,045,308 | 2025-11-07 17:12:44 |
| IONS | IONIS PHARMACEUTICALS INC | Geary Richard S | EVP, Chief Development Officer | 2025-11-03 | Sell | 1,680 | 75.05 | 126,091 | 2025-11-07 17:12:38 |
| IONS | IONIS PHARMACEUTICALS INC | Geary Richard S | EVP, Chief Development Officer | 2025-11-03 | Option Exercise | 1,680 | 58.68 | 98,576 | 2025-11-07 17:12:38 |
| IONS | IONIS PHARMACEUTICALS INC | WENDER JOSEPH H | Directior | 2025-10-30 | Sell | 28,000 | 74.02 | 2,072,578 | 2025-11-03 20:14:56 |
| IONS | IONIS PHARMACEUTICALS INC | LOSCALZO JOSEPH | Directior | 2025-10-31 | Sell | 16,000 | 75.10 | 1,201,669 | 2025-11-03 20:14:50 |
| IONS | IONIS PHARMACEUTICALS INC | LOSCALZO JOSEPH | Directior | 2025-10-31 | Option Exercise | 16,000 | 52.22 | 835,520 | 2025-11-03 20:14:50 |
| IONS | IONIS PHARMACEUTICALS INC | Geary Richard S | EVP, Chief Development Officer | 2025-10-31 | Sell | 90,929 | 75.11 | 6,829,432 | 2025-11-03 20:14:45 |
| IONS | IONIS PHARMACEUTICALS INC | Geary Richard S | EVP, Chief Development Officer | 2025-10-31 | Option Exercise | 70,929 | 58.84 | 4,173,213 | 2025-11-03 20:14:45 |
| IONS | IONIS PHARMACEUTICALS INC | Swayze Eric | EVP Research | 2025-10-15 | Sell | 53 | 73.62 | 3,902 | 2025-10-16 20:16:46 |
| IONS | IONIS PHARMACEUTICALS INC | Swayze Eric | EVP Research | 2025-10-15 | Option Exercise | 125 | 0.00 | 0 | 2025-10-16 20:16:46 |
| IONS | IONIS PHARMACEUTICALS INC | PARSHALL B LYNNE | Directior | 2025-10-15 | Sell | 5,000 | 71.74 | 358,722 | 2025-10-16 20:16:14 |
| IONS | IONIS PHARMACEUTICALS INC | Devers Shannon L. | EVP, Chief Human Resources Ofc | 2025-10-15 | Sell | 7,263 | 73.06 | 530,638 | 2025-10-16 20:16:08 |
| IONS | IONIS PHARMACEUTICALS INC | Devers Shannon L. | EVP, Chief Human Resources Ofc | 2025-10-15 | Option Exercise | 8,820 | 33.00 | 291,060 | 2025-10-16 20:16:08 |
| IONS | IONIS PHARMACEUTICALS INC | Birchler Brian | EVP, Corp and Development Ops | 2025-10-14 | Sell | 23,900 | 72.13 | 1,723,987 | 2025-10-16 20:15:51 |
| IONS | IONIS PHARMACEUTICALS INC | Birchler Brian | EVP, Corp and Development Ops | 2025-10-14 | Option Exercise | 23,900 | 53.77 | 1,285,103 | 2025-10-16 20:15:51 |
| IONS | IONIS PHARMACEUTICALS INC | Birchler Brian | EVP, Corp and Development Ops | 2025-10-14 | Sell | 23,900 | 72.13 | 1,723,987 | 2025-10-16 20:15:51 |
| IONS | IONIS PHARMACEUTICALS INC | Birchler Brian | EVP, Corp and Development Ops | 2025-10-14 | Option Exercise | 23,900 | 53.77 | 1,285,103 | 2025-10-16 20:15:51 |
| IONS | IONIS PHARMACEUTICALS INC | Swayze Eric | EVP Research | 2025-10-06 | Sell | 6,849 | 69.02 | 472,718 | 2025-10-08 18:37:06 |
| IONS | IONIS PHARMACEUTICALS INC | Swayze Eric | EVP Research | 2025-10-06 | Sell | 6,849 | 69.02 | 472,718 | 2025-10-08 18:37:06 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2025-10-06 | Sell | 13,441 | 69.74 | 937,338 | 2025-10-08 18:37:00 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2025-10-06 | Option Exercise | 10,200 | 52.87 | 539,274 | 2025-10-08 18:37:00 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2025-10-06 | Sell | 13,441 | 69.74 | 937,338 | 2025-10-08 18:37:00 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2025-10-06 | Option Exercise | 10,200 | 52.87 | 539,274 | 2025-10-08 18:37:00 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2025-10-06 | Sell | 437 | 69.26 | 30,268 | 2025-10-08 18:36:54 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2025-10-06 | Sell | 437 | 69.26 | 30,268 | 2025-10-08 18:36:54 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2025-10-06 | Sell | 1,625 | 69.37 | 112,725 | 2025-10-08 18:36:47 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2025-10-06 | Sell | 1,625 | 69.37 | 112,725 | 2025-10-08 18:36:47 |
| IONS | IONIS PHARMACEUTICALS INC | WENDER JOSEPH H | Directior | 2025-10-01 | Sell | 16,800 | 65.50 | 1,100,385 | 2025-10-02 19:36:16 |
| IONS | IONIS PHARMACEUTICALS INC | Swayze Eric | EVP Research | 2025-10-01 | Sell | 27,114 | 66.16 | 1,793,744 | 2025-10-02 19:36:11 |
| IONS | IONIS PHARMACEUTICALS INC | Swayze Eric | EVP Research | 2025-10-01 | Option Exercise | 27,114 | 53.77 | 1,457,920 | 2025-10-02 19:36:11 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2025-10-02 | Sell | 64,664 | 67.69 | 4,377,055 | 2025-10-02 19:35:57 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2025-10-02 | Option Exercise | 64,664 | 58.97 | 3,813,257 | 2025-10-02 19:35:57 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2025-10-02 | Sell | 15,000 | 68.01 | 1,020,210 | 2025-10-02 19:35:51 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2025-10-02 | Option Exercise | 15,000 | 31.80 | 477,000 | 2025-10-02 19:35:51 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2025-09-29 | Sell | 25,300 | 64.62 | 1,634,922 | 2025-10-01 16:55:36 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2025-09-29 | Option Exercise | 25,300 | 56.78 | 1,436,534 | 2025-10-01 16:55:36 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2025-09-29 | Sell | 25,300 | 64.62 | 1,634,922 | 2025-10-01 16:55:36 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2025-09-29 | Option Exercise | 25,300 | 56.78 | 1,436,534 | 2025-10-01 16:55:36 |
| IONS | IONIS PHARMACEUTICALS INC | Geary Richard S | EVP, Chief Development Officer | 2025-09-30 | Sell | 57,900 | 65.24 | 3,777,668 | 2025-10-01 16:55:29 |
| IONS | IONIS PHARMACEUTICALS INC | Geary Richard S | EVP, Chief Development Officer | 2025-09-30 | Option Exercise | 57,900 | 53.77 | 3,113,283 | 2025-10-01 16:55:29 |
| IONS | IONIS PHARMACEUTICALS INC | Geary Richard S | EVP, Chief Development Officer | 2025-09-30 | Sell | 57,900 | 65.24 | 3,777,668 | 2025-10-01 16:55:29 |
| IONS | IONIS PHARMACEUTICALS INC | Geary Richard S | EVP, Chief Development Officer | 2025-09-30 | Option Exercise | 57,900 | 53.77 | 3,113,283 | 2025-10-01 16:55:29 |
| IONS | IONIS PHARMACEUTICALS INC | HOUGEN ELIZABETH L | EVP, Finance & CFO | 2025-09-30 | Sell | 49,800 | 65.26 | 3,249,734 | 2025-10-01 16:55:20 |
| IONS | IONIS PHARMACEUTICALS INC | HOUGEN ELIZABETH L | EVP, Finance & CFO | 2025-09-30 | Option Exercise | 49,800 | 53.77 | 2,677,746 | 2025-10-01 16:55:20 |
| IONS | IONIS PHARMACEUTICALS INC | HOUGEN ELIZABETH L | EVP, Finance & CFO | 2025-09-30 | Sell | 49,800 | 65.26 | 3,249,734 | 2025-10-01 16:55:20 |
| IONS | IONIS PHARMACEUTICALS INC | HOUGEN ELIZABETH L | EVP, Finance & CFO | 2025-09-30 | Option Exercise | 49,800 | 53.77 | 2,677,746 | 2025-10-01 16:55:20 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2025-09-12 | Sell | 1,700 | 64.58 | 109,787 | 2025-09-16 16:56:38 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2025-09-12 | Option Exercise | 1,700 | 56.78 | 96,526 | 2025-09-16 16:56:38 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2025-09-09 | Sell | 11,950 | 62.16 | 742,838 | 2025-09-11 17:05:07 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2025-09-09 | Option Exercise | 11,950 | 31.80 | 380,010 | 2025-09-11 17:05:07 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2025-09-05 | Sell | 250 | 62.00 | 15,500 | 2025-09-09 18:30:41 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2025-09-05 | Option Exercise | 250 | 31.80 | 7,950 | 2025-09-09 18:30:41 |
| IONS | IONIS PHARMACEUTICALS INC | BENNETT C FRANK | EVP, Chief Scientific Officer | 2025-09-05 | Sell | 6,000 | 59.60 | 357,581 | 2025-09-09 18:30:25 |
| IONS | IONIS PHARMACEUTICALS INC | WENDER JOSEPH H | Directior | 2025-09-02 | Sell | 28,000 | 57.58 | 1,612,156 | 2025-09-04 20:40:10 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2025-09-03 | Sell | 203,814 | 60.32 | 12,294,703 | 2025-09-04 20:38:20 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2025-09-03 | Option Exercise | 203,814 | 44.32 | 9,032,039 | 2025-09-04 20:38:20 |
| IONS | IONIS PHARMACEUTICALS INC | Devers Shannon L. | EVP, Chief Human Resources Ofc | 2025-09-03 | Sell | 3,162 | 61.02 | 192,943 | 2025-09-04 20:36:34 |
| IONS | IONIS PHARMACEUTICALS INC | Devers Shannon L. | EVP, Chief Human Resources Ofc | 2025-09-03 | Option Exercise | 3,162 | 36.12 | 114,207 | 2025-09-04 20:36:34 |
| IONS | IONIS PHARMACEUTICALS INC | WENDER JOSEPH H | Directior | 2025-09-02 | Sell | 28,000 | 57.58 | 1,612,156 | 2025-09-04 20:34:45 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2025-09-03 | Sell | 32,800 | 59.34 | 1,946,220 | 2025-09-04 20:34:11 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2025-09-03 | Option Exercise | 32,800 | 31.80 | 1,043,040 | 2025-09-04 20:34:11 |
| IONS | IONIS PHARMACEUTICALS INC | Diaz Allene M. | Directior | 2025-08-22 | Sell | 1,427 | 42.53 | 60,687 | 2025-08-26 17:23:52 |
| IONS | IONIS PHARMACEUTICALS INC | BENNETT C FRANK | EVP, Chief Scientific Officer | 2025-08-18 | Sell | 10,000 | 43.98 | 439,776 | 2025-08-20 18:14:40 |
| IONS | IONIS PHARMACEUTICALS INC | BENNETT C FRANK | EVP, Chief Scientific Officer | 2025-08-18 | Option Exercise | 10,000 | 32.60 | 326,000 | 2025-08-20 18:14:40 |
| IONS | IONIS PHARMACEUTICALS INC | PARSHALL B LYNNE | Directior | 2025-08-06 | Sell | 5,000 | 41.93 | 209,646 | 2025-08-08 18:55:59 |
| IONS | IONIS PHARMACEUTICALS INC | Geary Richard S | EVP, Chief Development Officer | 2025-08-05 | Sell | 10,000 | 42.86 | 428,593 | 2025-08-06 18:44:16 |
| IONS | IONIS PHARMACEUTICALS INC | Schneider Eugene | EVP, Chf Clinical Develop Ofcr | 2025-08-04 | Sell | 9,549 | 42.80 | 408,701 | 2025-08-05 17:28:00 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2025-07-30 | Sell | 2,432 | 45.00 | 109,440 | 2025-08-01 16:06:41 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2025-07-30 | Option Exercise | 2,432 | 32.60 | 79,283 | 2025-08-01 16:06:41 |
| IONS | IONIS PHARMACEUTICALS INC | LOSCALZO JOSEPH | Directior | 2025-07-15 | Option Exercise | 4,079 | 0.00 | 0 | 2025-07-17 16:59:28 |
| IONS | IONIS PHARMACEUTICALS INC | YANG MICHAEL J. | Directior | 2025-07-15 | Option Exercise | 4,079 | 0.00 | 0 | 2025-07-17 16:54:38 |
| IONS | IONIS PHARMACEUTICALS INC | WENDER JOSEPH H | Directior | 2025-07-15 | Option Exercise | 4,079 | 0.00 | 0 | 2025-07-17 16:54:31 |
| IONS | IONIS PHARMACEUTICALS INC | PARSHALL B LYNNE | Directior | 2025-07-15 | Option Exercise | 4,079 | 0.00 | 0 | 2025-07-17 16:54:25 |
| IONS | IONIS PHARMACEUTICALS INC | HERMAN JOAN E | Directior | 2025-07-15 | Option Exercise | 4,079 | 0.00 | 0 | 2025-07-17 16:54:08 |
| IONS | IONIS PHARMACEUTICALS INC | Hayden Michael R | Directior | 2025-07-15 | Option Exercise | 4,079 | 0.00 | 0 | 2025-07-17 16:54:01 |
| IONS | IONIS PHARMACEUTICALS INC | Diaz Allene M. | Directior | 2025-07-15 | Option Exercise | 4,079 | 0.00 | 0 | 2025-07-17 16:53:54 |
| IONS | IONIS PHARMACEUTICALS INC | BERTHELSEN SPENCER R | Directior | 2025-07-15 | Option Exercise | 4,079 | 0.00 | 0 | 2025-07-17 16:53:48 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2025-07-11 | Sell | 1,160 | 41.74 | 48,416 | 2025-07-15 20:54:09 |
| IONS | IONIS PHARMACEUTICALS INC | Hayden Michael R | Directior | 2025-05-01 | Buy | 15,000 | 31.86 | 477,900 | 2025-05-02 16:38:26 |
| IONS | IONIS PHARMACEUTICALS INC | Birchler Brian | EVP, Corp and Development Ops | 2025-04-15 | Sell | 680 | 28.37 | 19,292 | 2025-04-17 16:53:27 |
| IONS | IONIS PHARMACEUTICALS INC | Birchler Brian | EVP, Corp and Development Ops | 2025-04-15 | Option Exercise | 1,875 | 0.00 | 0 | 2025-04-17 16:53:27 |
| IONS | IONIS PHARMACEUTICALS INC | Jenne Kyle | EVP, Chf GL Pdt Str Ofcr | 2025-04-15 | Sell | 3,016 | 28.36 | 85,534 | 2025-04-17 16:53:18 |
| IONS | IONIS PHARMACEUTICALS INC | Jenne Kyle | EVP, Chf GL Pdt Str Ofcr | 2025-04-15 | Option Exercise | 12,226 | 0.00 | 0 | 2025-04-17 16:53:18 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2025-04-15 | Sell | 3,928 | 28.40 | 111,555 | 2025-04-17 16:53:11 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2025-04-15 | Option Exercise | 10,837 | 0.00 | 0 | 2025-04-17 16:53:11 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2025-03-11 | Sell | 140 | 32.32 | 4,525 | 2025-03-13 16:45:26 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2025-02-20 | Sell | 1,207 | 32.35 | 39,046 | 2025-02-24 16:55:28 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2025-02-04 | Sell | 6,165 | 31.62 | 194,939 | 2025-02-06 18:27:25 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2025-02-04 | Sell | 38,843 | 31.65 | 1,229,463 | 2025-02-06 18:26:58 |
| IONS | IONIS PHARMACEUTICALS INC | Swayze Eric | EVP Research | 2025-01-30 | Sell | 1,367 | 32.31 | 44,162 | 2025-02-03 19:27:29 |
| IONS | IONIS PHARMACEUTICALS INC | Schneider Eugene | EVP, Chf Clinical Develop Ofcr | 2025-01-30 | Sell | 1,484 | 32.20 | 47,780 | 2025-02-03 19:27:17 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2025-01-30 | Sell | 1,406 | 32.49 | 45,685 | 2025-02-03 19:27:06 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2025-01-30 | Sell | 13,242 | 32.45 | 429,655 | 2025-02-03 19:26:55 |
| IONS | IONIS PHARMACEUTICALS INC | HOUGEN ELIZABETH L | EVP, Finance & CFO | 2025-01-30 | Sell | 1,523 | 32.44 | 49,404 | 2025-02-03 19:26:50 |
| IONS | IONIS PHARMACEUTICALS INC | Geary Richard S | EVP, Chief Development Officer | 2025-01-30 | Sell | 1,406 | 32.40 | 45,561 | 2025-02-03 19:26:42 |
| IONS | IONIS PHARMACEUTICALS INC | BENNETT C FRANK | EVP, Chief Scientific Officer | 2025-01-30 | Sell | 1,327 | 32.46 | 43,079 | 2025-02-03 19:26:31 |
| IONS | IONIS PHARMACEUTICALS INC | YANG MICHAEL J. | Directior | 2025-01-15 | Option Exercise | 1,931 | 0.00 | 0 | 2025-01-17 19:41:44 |
| IONS | IONIS PHARMACEUTICALS INC | Swayze Eric | EVP Research | 2025-01-15 | Sell | 7,176 | 32.84 | 235,678 | 2025-01-17 19:41:39 |
| IONS | IONIS PHARMACEUTICALS INC | Swayze Eric | EVP Research | 2025-01-15 | Option Exercise | 19,160 | 0.00 | 0 | 2025-01-17 19:41:39 |
| IONS | IONIS PHARMACEUTICALS INC | Schneider Eugene | EVP, Chf Clinical Develop Ofcr | 2025-01-15 | Sell | 6,523 | 32.79 | 213,889 | 2025-01-17 19:41:34 |
| IONS | IONIS PHARMACEUTICALS INC | Schneider Eugene | EVP, Chf Clinical Develop Ofcr | 2025-01-15 | Option Exercise | 17,372 | 0.00 | 0 | 2025-01-17 19:41:34 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2025-01-15 | Sell | 7,360 | 32.83 | 241,629 | 2025-01-17 19:41:16 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2025-01-15 | Option Exercise | 19,690 | 0.00 | 0 | 2025-01-17 19:41:16 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2025-01-15 | Sell | 33,445 | 32.63 | 1,091,444 | 2025-01-17 19:41:07 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2025-01-15 | Option Exercise | 73,448 | 0.00 | 0 | 2025-01-17 19:41:07 |
| IONS | IONIS PHARMACEUTICALS INC | HOUGEN ELIZABETH L | EVP, Finance & CFO | 2025-01-15 | Sell | 8,870 | 32.81 | 290,989 | 2025-01-17 19:40:35 |
| IONS | IONIS PHARMACEUTICALS INC | HOUGEN ELIZABETH L | EVP, Finance & CFO | 2025-01-15 | Option Exercise | 23,887 | 0.00 | 0 | 2025-01-17 19:40:35 |
| IONS | IONIS PHARMACEUTICALS INC | Geary Richard S | EVP, Chief Development Officer | 2025-01-15 | Sell | 7,072 | 32.86 | 232,407 | 2025-01-17 19:40:28 |
| IONS | IONIS PHARMACEUTICALS INC | Geary Richard S | EVP, Chief Development Officer | 2025-01-15 | Option Exercise | 18,901 | 0.00 | 0 | 2025-01-17 19:40:28 |
| IONS | IONIS PHARMACEUTICALS INC | Devers Shannon L. | EVP, Chief Human Resources Ofc | 2025-01-15 | Sell | 4,267 | 32.78 | 139,855 | 2025-01-17 19:40:20 |
| IONS | IONIS PHARMACEUTICALS INC | Devers Shannon L. | EVP, Chief Human Resources Ofc | 2025-01-15 | Option Exercise | 12,295 | 0.00 | 0 | 2025-01-17 19:40:20 |
| IONS | IONIS PHARMACEUTICALS INC | Birchler Brian | EVP, Corp and Development Ops | 2025-01-15 | Sell | 5,400 | 32.70 | 176,580 | 2025-01-17 19:40:15 |
| IONS | IONIS PHARMACEUTICALS INC | Birchler Brian | EVP, Corp and Development Ops | 2025-01-15 | Option Exercise | 14,283 | 0.00 | 0 | 2025-01-17 19:40:15 |
| IONS | IONIS PHARMACEUTICALS INC | BENNETT C FRANK | EVP, Chief Scientific Officer | 2025-01-15 | Sell | 6,752 | 32.90 | 222,114 | 2025-01-17 19:40:07 |
| IONS | IONIS PHARMACEUTICALS INC | BENNETT C FRANK | EVP, Chief Scientific Officer | 2025-01-15 | Option Exercise | 18,011 | 0.00 | 0 | 2025-01-17 19:40:07 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2025-01-15 | Sell | 4,430 | 32.70 | 144,861 | 2025-01-17 19:40:01 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2025-01-15 | Option Exercise | 11,247 | 0.00 | 0 | 2025-01-17 19:40:01 |
| IONS | IONIS PHARMACEUTICALS INC | Hayden Michael R | Directior | 2024-12-23 | Buy | 5,000 | 36.22 | 181,079 | 2024-12-26 16:57:52 |
| IONS | IONIS PHARMACEUTICALS INC | Swayze Eric | EVP Research | 2024-11-12 | Sell | 1,194 | 37.92 | 45,278 | 2024-11-14 17:30:53 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2024-11-12 | Sell | 6,630 | 38.05 | 252,294 | 2024-11-14 17:30:47 |
| IONS | IONIS PHARMACEUTICALS INC | LOSCALZO JOSEPH | Directior | 2024-11-12 | Sell | 13,508 | 37.86 | 511,426 | 2024-11-14 17:30:42 |
| IONS | IONIS PHARMACEUTICALS INC | Swayze Eric | EVP Research | 2024-10-15 | Sell | 53 | 38.31 | 2,031 | 2024-10-17 18:42:01 |
| IONS | IONIS PHARMACEUTICALS INC | Swayze Eric | EVP Research | 2024-10-15 | Option Exercise | 125 | 0.00 | 0 | 2024-10-17 18:42:01 |
| IONS | IONIS PHARMACEUTICALS INC | WENDER JOSEPH H | Directior | 2024-07-15 | Option Exercise | 4,677 | 0.00 | 0 | 2024-07-17 17:03:14 |
| IONS | IONIS PHARMACEUTICALS INC | PARSHALL B LYNNE | Directior | 2024-07-15 | Option Exercise | 4,677 | 0.00 | 0 | 2024-07-17 17:03:07 |
| IONS | IONIS PHARMACEUTICALS INC | LOSCALZO JOSEPH | Directior | 2024-07-15 | Option Exercise | 4,677 | 0.00 | 0 | 2024-07-17 17:03:02 |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Directior | 2024-07-16 | Sell | 12,000 | 50.00 | 600,000 | 2024-07-17 17:02:56 |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Directior | 2024-07-16 | Option Exercise | 12,000 | 24.42 | 293,040 | 2024-07-17 17:02:56 |
| IONS | IONIS PHARMACEUTICALS INC | HERMAN JOAN E | Directior | 2024-07-15 | Option Exercise | 4,677 | 0.00 | 0 | 2024-07-17 17:02:41 |
| IONS | IONIS PHARMACEUTICALS INC | Diaz Allene M. | Directior | 2024-07-15 | Sell | 1,637 | 49.49 | 81,019 | 2024-07-17 17:02:35 |
| IONS | IONIS PHARMACEUTICALS INC | Diaz Allene M. | Directior | 2024-07-15 | Option Exercise | 4,677 | 0.00 | 0 | 2024-07-17 17:02:35 |
| IONS | IONIS PHARMACEUTICALS INC | BERTHELSEN SPENCER R | Directior | 2024-07-15 | Option Exercise | 4,677 | 0.00 | 0 | 2024-07-17 17:02:26 |
| IONS | IONIS PHARMACEUTICALS INC | BERTHELSEN SPENCER R | Directior | 2024-06-17 | Sell | 16,000 | 40.29 | 644,640 | 2024-06-20 17:52:19 |
| IONS | IONIS PHARMACEUTICALS INC | BERTHELSEN SPENCER R | Directior | 2024-06-17 | Option Exercise | 16,000 | 35.53 | 568,480 | 2024-06-20 17:52:19 |
| IONS | IONIS PHARMACEUTICALS INC | WENDER JOSEPH H | Directior | 2024-05-09 | Option Exercise | 16,000 | 35.53 | 568,480 | 2024-05-13 17:25:49 |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Directior | 2024-05-03 | Sell | 6,000 | 42.71 | 256,277 | 2024-05-07 16:55:46 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2024-04-15 | Sell | 4,006 | 41.60 | 166,641 | 2024-04-17 17:19:22 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2024-04-15 | Option Exercise | 10,838 | 0.00 | 0 | 2024-04-17 17:19:22 |
| IONS | IONIS PHARMACEUTICALS INC | Birchler Brian | EVP, Corp and Development Ops | 2024-04-15 | Sell | 905 | 41.66 | 37,698 | 2024-04-17 17:16:37 |
| IONS | IONIS PHARMACEUTICALS INC | Birchler Brian | EVP, Corp and Development Ops | 2024-04-15 | Option Exercise | 1,875 | 0.00 | 0 | 2024-04-17 17:16:37 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2024-02-16 | Sell | 387 | 44.49 | 17,219 | 2024-02-16 19:47:19 |
| IONS | IONIS PHARMACEUTICALS INC | Swayze Eric | EVP Research | 2024-01-31 | Sell | 12,680 | 51.63 | 654,709 | 2024-02-02 19:55:47 |
| IONS | IONIS PHARMACEUTICALS INC | Schneider Eugene | EVP, Chf Clinical Develop Ofcr | 2024-02-01 | Sell | 2,071 | 49.59 | 102,701 | 2024-02-02 19:55:40 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2024-02-01 | Sell | 1,961 | 49.67 | 97,410 | 2024-02-02 19:55:32 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2024-02-01 | Sell | 23,501 | 49.37 | 1,160,303 | 2024-02-02 19:55:25 |
| IONS | IONIS PHARMACEUTICALS INC | HOUGEN ELIZABETH L | EVP, Finance & CFO | 2024-02-01 | Sell | 2,125 | 49.54 | 105,272 | 2024-02-02 19:55:15 |
| IONS | IONIS PHARMACEUTICALS INC | Geary Richard S | EVP, Chief Development Officer | 2024-02-01 | Sell | 1,961 | 50.04 | 98,135 | 2024-02-02 19:54:57 |
| IONS | IONIS PHARMACEUTICALS INC | Cadoret-Manier Onaiza | EVP, Chf GL Pdt Str & Oper Ofc | 2024-02-01 | Sell | 2,125 | 49.60 | 105,404 | 2024-02-02 19:54:54 |
| IONS | IONIS PHARMACEUTICALS INC | BENNETT C FRANK | EVP, Chief Scientific Officer | 2024-02-01 | Sell | 1,853 | 49.52 | 91,752 | 2024-02-02 19:54:45 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2024-01-25 | Sell | 2,285 | 51.75 | 118,249 | 2024-01-29 17:34:18 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2024-01-25 | Sell | 6,450 | 51.75 | 333,788 | 2024-01-29 17:34:07 |
| IONS | IONIS PHARMACEUTICALS INC | Cadoret-Manier Onaiza | EVP, Chf GL Pdt Str & Oper Ofc | 2024-01-16 | Sell | 5,564 | 50.42 | 280,520 | 2024-01-18 18:07:45 |
| IONS | IONIS PHARMACEUTICALS INC | Cadoret-Manier Onaiza | EVP, Chf GL Pdt Str & Oper Ofc | 2024-01-16 | Option Exercise | 15,062 | 0.00 | 0 | 2024-01-18 18:07:45 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2024-01-16 | Sell | 7,744 | 50.42 | 390,429 | 2024-01-18 17:59:48 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2024-01-16 | Option Exercise | 20,641 | 0.00 | 0 | 2024-01-18 17:59:48 |
| IONS | IONIS PHARMACEUTICALS INC | Birchler Brian | EVP, Corp and Development Ops | 2024-01-16 | Sell | 4,497 | 50.42 | 226,725 | 2024-01-18 17:55:44 |
| IONS | IONIS PHARMACEUTICALS INC | Birchler Brian | EVP, Corp and Development Ops | 2024-01-16 | Option Exercise | 12,080 | 0.00 | 0 | 2024-01-18 17:55:44 |
| IONS | IONIS PHARMACEUTICALS INC | Swayze Eric | EVP Research | 2024-01-16 | Sell | 6,305 | 50.42 | 317,879 | 2024-01-18 17:49:18 |
