| Lastest Insider Transactions Of IONIS PHARMACEUTICALS INC ( IONS ) |
| Symbol | Company Name | Insider Name | Title | Date | Transation | Share | Price | Amount | File Date |
| IONS | IONIS PHARMACEUTICALS INC | Hayden Michael R | Directior | 2026-07-30 | Buy | 20,000 | 52.94 | 1,058,700 | 2026-07-31 16:42:12 |
| IONS | IONIS PHARMACEUTICALS INC | HERMAN JOAN E | Directior | 2026-07-15 | Option Exercise | 5,220 | 0.00 | 0 | 2026-07-17 17:12:37 |
| IONS | IONIS PHARMACEUTICALS INC | BERTHELSEN SPENCER R | Directior | 2026-07-15 | Option Exercise | 5,220 | 0.00 | 0 | 2026-07-17 17:12:26 |
| IONS | IONIS PHARMACEUTICALS INC | BENNETT C FRANK | EVP, Chief Scientific Officer | 2026-07-07 | Sell | 20,536 | 84.95 | 1,744,623 | 2026-07-09 19:26:31 |
| IONS | IONIS PHARMACEUTICALS INC | Diaz Allene M. | Directior | 2026-07-07 | Sell | 10,111 | 85.42 | 863,637 | 2026-07-09 18:07:56 |
| IONS | IONIS PHARMACEUTICALS INC | Diaz Allene M. | Directior | 2026-07-07 | Option Exercise | 10,111 | 47.11 | 476,329 | 2026-07-09 18:07:56 |
| IONS | IONIS PHARMACEUTICALS INC | Kordasiewicz Holly B. | EVP, Chief Development Officer | 2026-07-07 | Sell | 362 | 84.30 | 30,517 | 2026-07-09 18:07:45 |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Directior | 2026-07-01 | Sell | 11,518 | 79.04 | 910,416 | 2026-07-06 18:49:29 |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Directior | 2026-07-01 | Option Exercise | 11,518 | 39.94 | 460,029 | 2026-07-06 18:49:29 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2026-06-26 | Sell | 5,635 | 80.16 | 451,699 | 2026-06-30 17:48:32 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2026-06-26 | Option Exercise | 5,635 | 49.19 | 277,181 | 2026-06-30 17:48:32 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2026-06-26 | Sell | 3,069 | 80.00 | 245,520 | 2026-06-30 17:48:21 |
| IONS | IONIS PHARMACEUTICALS INC | Schneider Eugene | EVP, Chf Clinical Develop Ofcr | 2026-06-26 | Sell | 26,000 | 81.05 | 2,107,196 | 2026-06-30 17:48:12 |
| IONS | IONIS PHARMACEUTICALS INC | Schneider Eugene | EVP, Chf Clinical Develop Ofcr | 2026-06-26 | Option Exercise | 26,000 | 60.89 | 1,583,140 | 2026-06-30 17:48:12 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2026-06-24 | Sell | 85,637 | 79.70 | 6,825,524 | 2026-06-26 19:09:50 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2026-06-24 | Option Exercise | 85,637 | 46.72 | 4,000,766 | 2026-06-26 19:09:50 |
| IONS | IONIS PHARMACEUTICALS INC | Swayze Eric | EVP Research | 2026-06-25 | Sell | 10,602 | 79.18 | 839,492 | 2026-06-26 19:09:43 |
| IONS | IONIS PHARMACEUTICALS INC | Kordasiewicz Holly B. | EVP, Chief Development Officer | 2026-06-12 | Sell | 60,846 | 73.41 | 4,466,428 | 2026-06-16 17:26:18 |
| IONS | IONIS PHARMACEUTICALS INC | Kordasiewicz Holly B. | EVP, Chief Development Officer | 2026-06-12 | Option Exercise | 60,846 | 53.97 | 3,283,665 | 2026-06-16 17:26:18 |
| IONS | IONIS PHARMACEUTICALS INC | BERTHELSEN SPENCER R | Directior | 2026-06-15 | Sell | 8,000 | 73.49 | 587,920 | 2026-06-16 17:26:11 |
| IONS | IONIS PHARMACEUTICALS INC | BERTHELSEN SPENCER R | Directior | 2026-06-15 | Option Exercise | 8,000 | 24.42 | 195,360 | 2026-06-16 17:26:11 |
| IONS | IONIS PHARMACEUTICALS INC | BERTHELSEN SPENCER R | Directior | 2026-06-01 | Sell | 8,000 | 75.67 | 605,360 | 2026-06-03 17:34:36 |
| IONS | IONIS PHARMACEUTICALS INC | BERTHELSEN SPENCER R | Directior | 2026-06-01 | Option Exercise | 8,000 | 24.42 | 195,360 | 2026-06-03 17:34:36 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2026-05-13 | Sell | 4,536 | 78.49 | 356,012 | 2026-05-15 18:15:03 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2026-05-13 | Option Exercise | 4,536 | 32.60 | 147,874 | 2026-05-15 18:15:03 |
| IONS | IONIS PHARMACEUTICALS INC | LOSCALZO JOSEPH | Directior | 2026-05-04 | Sell | 77,289 | 75.06 | 5,801,226 | 2026-05-06 17:27:00 |
| IONS | IONIS PHARMACEUTICALS INC | LOSCALZO JOSEPH | Directior | 2026-05-04 | Option Exercise | 77,289 | 48.74 | 3,767,309 | 2026-05-06 17:27:00 |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Directior | 2026-05-01 | Sell | 10,111 | 73.51 | 743,238 | 2026-05-05 16:30:25 |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Directior | 2026-05-01 | Option Exercise | 10,111 | 47.11 | 476,329 | 2026-05-05 16:30:25 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2026-04-28 | Sell | 1,626 | 71.79 | 116,727 | 2026-04-30 16:21:24 |
| IONS | IONIS PHARMACEUTICALS INC | PARSHALL B LYNNE | Directior | 2026-04-15 | Sell | 5,000 | 76.27 | 381,367 | 2026-04-17 19:19:39 |
| IONS | IONIS PHARMACEUTICALS INC | Jenne Kyle | EVP, Chf GL Pdt Str Ofcr | 2026-04-15 | Sell | 4,902 | 75.17 | 368,488 | 2026-04-17 19:19:32 |
| IONS | IONIS PHARMACEUTICALS INC | Jenne Kyle | EVP, Chf GL Pdt Str Ofcr | 2026-04-15 | Option Exercise | 12,226 | 0.00 | 0 | 2026-04-17 19:19:32 |
| IONS | IONIS PHARMACEUTICALS INC | Birchler Brian | EVP, Corp and Development Ops | 2026-04-15 | Sell | 973 | 75.04 | 73,016 | 2026-04-17 19:19:21 |
| IONS | IONIS PHARMACEUTICALS INC | Birchler Brian | EVP, Corp and Development Ops | 2026-04-15 | Option Exercise | 1,875 | 0.00 | 0 | 2026-04-17 19:19:21 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2026-04-15 | Sell | 5,619 | 74.56 | 418,953 | 2026-04-17 19:19:15 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2026-04-15 | Option Exercise | 10,837 | 0.00 | 0 | 2026-04-17 19:19:15 |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Directior | 2026-04-01 | Sell | 22,321 | 75.55 | 1,686,302 | 2026-04-02 19:43:46 |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Directior | 2026-04-01 | Option Exercise | 22,321 | 39.46 | 880,707 | 2026-04-02 19:43:46 |
| IONS | IONIS PHARMACEUTICALS INC | Devers Shannon L. | EVP, Chief Human Resources Ofc | 2026-04-02 | Sell | 6,193 | 74.05 | 458,613 | 2026-04-02 19:43:36 |
| IONS | IONIS PHARMACEUTICALS INC | Schneider Eugene | EVP, Chf Clinical Develop Ofcr | 2026-03-19 | Sell | 5,812 | 70.97 | 412,486 | 2026-03-23 19:36:40 |
| IONS | IONIS PHARMACEUTICALS INC | HOUGEN ELIZABETH L | EVP, Finance & CFO | 2026-03-16 | Sell | 225,220 | 72.43 | 16,313,676 | 2026-03-18 17:19:18 |
| IONS | IONIS PHARMACEUTICALS INC | HOUGEN ELIZABETH L | EVP, Finance & CFO | 2026-03-16 | Option Exercise | 174,999 | 51.37 | 8,989,092 | 2026-03-18 17:19:18 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2026-03-09 | Sell | 10,148 | 75.25 | 763,662 | 2026-03-11 16:19:14 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2026-03-09 | Sell | 160,773 | 75.35 | 12,114,155 | 2026-03-11 16:19:03 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2026-03-09 | Option Exercise | 148,454 | 60.89 | 9,039,364 | 2026-03-11 16:19:03 |
| IONS | IONIS PHARMACEUTICALS INC | Jenne Kyle | EVP, Chf GL Pdt Str Ofcr | 2026-03-10 | Sell | 37,277 | 75.85 | 2,827,325 | 2026-03-11 16:18:53 |
| IONS | IONIS PHARMACEUTICALS INC | Jenne Kyle | EVP, Chf GL Pdt Str Ofcr | 2026-03-10 | Option Exercise | 37,277 | 44.67 | 1,665,128 | 2026-03-11 16:18:53 |
| IONS | IONIS PHARMACEUTICALS INC | LOSCALZO JOSEPH | Directior | 2026-03-03 | Sell | 1,032 | 80.26 | 82,833 | 2026-03-05 18:14:30 |
| IONS | IONIS PHARMACEUTICALS INC | LOSCALZO JOSEPH | Directior | 2026-03-03 | Option Exercise | 1,032 | 38.06 | 39,278 | 2026-03-05 18:14:30 |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Directior | 2026-03-03 | Sell | 21,332 | 79.51 | 1,696,181 | 2026-03-05 18:14:23 |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Directior | 2026-03-03 | Option Exercise | 16,000 | 40.76 | 652,120 | 2026-03-05 18:14:23 |
| IONS | IONIS PHARMACEUTICALS INC | Diaz Allene M. | Directior | 2026-03-03 | Sell | 54,878 | 79.35 | 4,354,428 | 2026-03-05 18:14:15 |
| IONS | IONIS PHARMACEUTICALS INC | Diaz Allene M. | Directior | 2026-03-03 | Option Exercise | 40,321 | 39.72 | 1,601,607 | 2026-03-05 18:14:15 |
| IONS | IONIS PHARMACEUTICALS INC | Devers Shannon L. | EVP, Chief Human Resources Ofc | 2026-03-03 | Sell | 20,106 | 79.40 | 1,596,433 | 2026-03-05 18:14:06 |
| IONS | IONIS PHARMACEUTICALS INC | Devers Shannon L. | EVP, Chief Human Resources Ofc | 2026-03-03 | Option Exercise | 20,106 | 35.97 | 723,254 | 2026-03-05 18:14:06 |
| IONS | IONIS PHARMACEUTICALS INC | BENNETT C FRANK | EVP, Chief Scientific Officer | 2026-03-03 | Sell | 85,089 | 79.23 | 6,741,669 | 2026-03-05 18:13:59 |
| IONS | IONIS PHARMACEUTICALS INC | BENNETT C FRANK | EVP, Chief Scientific Officer | 2026-03-03 | Option Exercise | 65,089 | 53.73 | 3,497,531 | 2026-03-05 18:13:59 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2026-03-03 | Sell | 6,659 | 79.74 | 530,987 | 2026-03-05 18:13:53 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2026-03-03 | Option Exercise | 2,138 | 44.57 | 95,281 | 2026-03-05 18:13:53 |
| IONS | IONIS PHARMACEUTICALS INC | Swayze Eric | EVP Research | 2026-02-13 | Sell | 15,642 | 81.76 | 1,278,914 | 2026-02-13 19:40:24 |
| IONS | IONIS PHARMACEUTICALS INC | PARSHALL B LYNNE | Directior | 2026-02-11 | Sell | 5,000 | 82.72 | 413,589 | 2026-02-13 19:40:10 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2026-02-06 | Sell | 29,430 | 85.79 | 2,524,820 | 2026-02-10 17:04:29 |
| IONS | IONIS PHARMACEUTICALS INC | BENNETT C FRANK | EVP, Chief Scientific Officer | 2026-02-02 | Sell | 85,089 | 82.93 | 7,056,216 | 2026-02-04 16:06:04 |
| IONS | IONIS PHARMACEUTICALS INC | BENNETT C FRANK | EVP, Chief Scientific Officer | 2026-02-02 | Option Exercise | 65,089 | 53.73 | 3,497,531 | 2026-02-04 16:06:04 |
| IONS | IONIS PHARMACEUTICALS INC | Swayze Eric | EVP Research | 2026-01-29 | Sell | 6,179 | 82.93 | 512,446 | 2026-02-02 20:52:12 |
| IONS | IONIS PHARMACEUTICALS INC | Schneider Eugene | EVP, Chf Clinical Develop Ofcr | 2026-01-29 | Sell | 6,179 | 83.45 | 515,630 | 2026-02-02 20:52:06 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2026-01-29 | Sell | 6,179 | 83.53 | 516,154 | 2026-02-02 20:51:59 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2026-01-29 | Sell | 62,970 | 82.72 | 5,208,979 | 2026-02-02 20:51:49 |
| IONS | IONIS PHARMACEUTICALS INC | HOUGEN ELIZABETH L | EVP, Finance & CFO | 2026-01-29 | Sell | 6,988 | 83.24 | 581,702 | 2026-02-02 20:51:38 |
| IONS | IONIS PHARMACEUTICALS INC | Birchler Brian | EVP, Corp and Development Ops | 2026-01-29 | Sell | 6,179 | 83.03 | 513,048 | 2026-02-02 20:51:32 |
| IONS | IONIS PHARMACEUTICALS INC | BENNETT C FRANK | EVP, Chief Scientific Officer | 2026-01-29 | Sell | 5,885 | 82.95 | 488,141 | 2026-02-02 20:51:27 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2026-01-29 | Sell | 5,296 | 82.96 | 439,364 | 2026-02-02 20:51:21 |
| IONS | IONIS PHARMACEUTICALS INC | Devers Shannon L. | EVP, Chief Human Resources Ofc | 2026-01-22 | Sell | 3,977 | 81.34 | 323,490 | 2026-01-23 17:51:50 |
| IONS | IONIS PHARMACEUTICALS INC | YANG MICHAEL J. | Directior | 2026-01-15 | Option Exercise | 1,930 | 0.00 | 0 | 2026-01-20 20:21:43 |
| IONS | IONIS PHARMACEUTICALS INC | Swayze Eric | EVP Research | 2026-01-15 | Sell | 9,933 | 75.34 | 748,383 | 2026-01-20 20:21:37 |
| IONS | IONIS PHARMACEUTICALS INC | Swayze Eric | EVP Research | 2026-01-15 | Option Exercise | 21,477 | 0.00 | 0 | 2026-01-20 20:21:37 |
| IONS | IONIS PHARMACEUTICALS INC | Schneider Eugene | EVP, Chf Clinical Develop Ofcr | 2026-01-15 | Sell | 9,302 | 75.59 | 703,138 | 2026-01-20 20:21:31 |
| IONS | IONIS PHARMACEUTICALS INC | Schneider Eugene | EVP, Chf Clinical Develop Ofcr | 2026-01-15 | Option Exercise | 21,685 | 0.00 | 0 | 2026-01-20 20:21:31 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2026-01-15 | Sell | 9,191 | 75.84 | 697,045 | 2026-01-20 20:20:29 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2026-01-15 | Option Exercise | 21,473 | 0.00 | 0 | 2026-01-20 20:20:29 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2026-01-15 | Sell | 44,034 | 74.82 | 3,294,624 | 2026-01-20 20:20:23 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2026-01-15 | Option Exercise | 89,145 | 0.00 | 0 | 2026-01-20 20:20:23 |
| IONS | IONIS PHARMACEUTICALS INC | Kordasiewicz Holly B. | EVP, Chief Development Officer | 2026-01-15 | Sell | 4,141 | 75.66 | 313,308 | 2026-01-20 20:18:47 |
| IONS | IONIS PHARMACEUTICALS INC | Kordasiewicz Holly B. | EVP, Chief Development Officer | 2026-01-15 | Option Exercise | 11,119 | 0.00 | 0 | 2026-01-20 20:18:47 |
| IONS | IONIS PHARMACEUTICALS INC | Jenne Kyle | EVP, Chf GL Pdt Str Ofcr | 2026-01-15 | Sell | 1,823 | 75.96 | 138,475 | 2026-01-20 20:18:39 |
| IONS | IONIS PHARMACEUTICALS INC | Jenne Kyle | EVP, Chf GL Pdt Str Ofcr | 2026-01-15 | Option Exercise | 7,013 | 0.00 | 0 | 2026-01-20 20:18:39 |
| IONS | IONIS PHARMACEUTICALS INC | HOUGEN ELIZABETH L | EVP, Finance & CFO | 2026-01-15 | Sell | 12,922 | 75.22 | 971,993 | 2026-01-20 20:18:32 |
| IONS | IONIS PHARMACEUTICALS INC | HOUGEN ELIZABETH L | EVP, Finance & CFO | 2026-01-15 | Option Exercise | 28,729 | 0.00 | 0 | 2026-01-20 20:18:32 |
| IONS | IONIS PHARMACEUTICALS INC | HOUGEN ELIZABETH L | EVP, Finance & CFO | 2026-01-15 | Sell | 12,922 | 75.22 | 971,993 | 2026-01-20 20:18:32 |
| IONS | IONIS PHARMACEUTICALS INC | HOUGEN ELIZABETH L | EVP, Finance & CFO | 2026-01-15 | Option Exercise | 28,729 | 0.00 | 0 | 2026-01-20 20:18:32 |
| IONS | IONIS PHARMACEUTICALS INC | Devers Shannon L. | EVP, Chief Human Resources Ofc | 2026-01-15 | Sell | 8,353 | 75.95 | 634,410 | 2026-01-20 20:18:26 |
| IONS | IONIS PHARMACEUTICALS INC | Devers Shannon L. | EVP, Chief Human Resources Ofc | 2026-01-15 | Option Exercise | 17,377 | 0.00 | 0 | 2026-01-20 20:18:26 |
| IONS | IONIS PHARMACEUTICALS INC | Birchler Brian | EVP, Corp and Development Ops | 2026-01-15 | Sell | 8,480 | 75.11 | 636,933 | 2026-01-20 20:18:16 |
| IONS | IONIS PHARMACEUTICALS INC | Birchler Brian | EVP, Corp and Development Ops | 2026-01-15 | Option Exercise | 20,089 | 0.00 | 0 | 2026-01-20 20:18:16 |
| IONS | IONIS PHARMACEUTICALS INC | BENNETT C FRANK | EVP, Chief Scientific Officer | 2026-01-15 | Sell | 8,977 | 75.15 | 674,622 | 2026-01-20 20:18:10 |
| IONS | IONIS PHARMACEUTICALS INC | BENNETT C FRANK | EVP, Chief Scientific Officer | 2026-01-15 | Option Exercise | 21,055 | 0.00 | 0 | 2026-01-20 20:18:10 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2026-01-15 | Sell | 8,056 | 75.75 | 610,277 | 2026-01-20 20:18:04 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2026-01-15 | Option Exercise | 19,887 | 0.00 | 0 | 2026-01-20 20:18:04 |
| IONS | IONIS PHARMACEUTICALS INC | Devers Shannon L. | EVP, Chief Human Resources Ofc | 2026-01-07 | Sell | 44,199 | 85.08 | 3,760,578 | 2026-01-09 17:08:28 |
| IONS | IONIS PHARMACEUTICALS INC | Devers Shannon L. | EVP, Chief Human Resources Ofc | 2026-01-07 | Option Exercise | 44,199 | 51.25 | 2,265,415 | 2026-01-09 17:08:28 |
| IONS | IONIS PHARMACEUTICALS INC | Swayze Eric | EVP Research | 2026-01-02 | Sell | 23,463 | 79.12 | 1,856,325 | 2026-01-06 17:35:26 |
| IONS | IONIS PHARMACEUTICALS INC | Swayze Eric | EVP Research | 2026-01-02 | Option Exercise | 23,463 | 60.89 | 1,428,662 | 2026-01-06 17:35:26 |
| IONS | IONIS PHARMACEUTICALS INC | WENDER JOSEPH H | Directior | 2025-12-01 | Sell | 28,000 | 80.82 | 2,262,848 | 2025-12-03 19:01:07 |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Directior | 2025-11-25 | Sell | 12,000 | 80.00 | 960,000 | 2025-11-28 17:51:58 |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Directior | 2025-11-25 | Option Exercise | 12,000 | 0.00 | 0 | 2025-11-28 17:51:58 |
| IONS | IONIS PHARMACEUTICALS INC | Devers Shannon L. | EVP, Chief Human Resources Ofc | 2025-11-25 | Sell | 16,777 | 80.91 | 1,357,442 | 2025-11-28 17:51:52 |
| IONS | IONIS PHARMACEUTICALS INC | Devers Shannon L. | EVP, Chief Human Resources Ofc | 2025-11-25 | Option Exercise | 16,777 | 53.77 | 902,099 | 2025-11-28 17:51:52 |
| IONS | IONIS PHARMACEUTICALS INC | Devers Shannon L. | EVP, Chief Human Resources Ofc | 2025-11-25 | Sell | 16,777 | 80.91 | 1,357,442 | 2025-11-28 17:51:52 |
| IONS | IONIS PHARMACEUTICALS INC | Devers Shannon L. | EVP, Chief Human Resources Ofc | 2025-11-25 | Option Exercise | 16,777 | 53.77 | 902,099 | 2025-11-28 17:51:52 |
| IONS | IONIS PHARMACEUTICALS INC | WENDER JOSEPH H | Directior | 2025-11-18 | Option Exercise | 16,000 | 24.42 | 390,720 | 2025-11-20 17:12:23 |
| IONS | IONIS PHARMACEUTICALS INC | HERMAN JOAN E | Directior | 2025-11-19 | Sell | 44,000 | 72.13 | 3,173,830 | 2025-11-20 17:12:11 |
| IONS | IONIS PHARMACEUTICALS INC | HERMAN JOAN E | Directior | 2025-11-19 | Option Exercise | 44,000 | 57.40 | 2,525,400 | 2025-11-20 17:12:11 |
| IONS | IONIS PHARMACEUTICALS INC | Birchler Brian | EVP, Corp and Development Ops | 2025-11-06 | Sell | 8,000 | 76.17 | 609,379 | 2025-11-07 17:13:09 |
| IONS | IONIS PHARMACEUTICALS INC | Geary Richard S | EVP, Chief Development Officer | 2025-11-05 | Sell | 34,639 | 75.69 | 2,621,816 | 2025-11-07 17:12:44 |
| IONS | IONIS PHARMACEUTICALS INC | Geary Richard S | EVP, Chief Development Officer | 2025-11-05 | Option Exercise | 34,639 | 59.05 | 2,045,308 | 2025-11-07 17:12:44 |
| IONS | IONIS PHARMACEUTICALS INC | Geary Richard S | EVP, Chief Development Officer | 2025-11-03 | Sell | 1,680 | 75.05 | 126,091 | 2025-11-07 17:12:38 |
| IONS | IONIS PHARMACEUTICALS INC | Geary Richard S | EVP, Chief Development Officer | 2025-11-03 | Option Exercise | 1,680 | 58.68 | 98,576 | 2025-11-07 17:12:38 |
| IONS | IONIS PHARMACEUTICALS INC | WENDER JOSEPH H | Directior | 2025-10-30 | Sell | 28,000 | 74.02 | 2,072,578 | 2025-11-03 20:14:56 |
| IONS | IONIS PHARMACEUTICALS INC | LOSCALZO JOSEPH | Directior | 2025-10-31 | Sell | 16,000 | 75.10 | 1,201,669 | 2025-11-03 20:14:50 |
| IONS | IONIS PHARMACEUTICALS INC | LOSCALZO JOSEPH | Directior | 2025-10-31 | Option Exercise | 16,000 | 52.22 | 835,520 | 2025-11-03 20:14:50 |
| IONS | IONIS PHARMACEUTICALS INC | Geary Richard S | EVP, Chief Development Officer | 2025-10-31 | Sell | 90,929 | 75.11 | 6,829,432 | 2025-11-03 20:14:45 |
| IONS | IONIS PHARMACEUTICALS INC | Geary Richard S | EVP, Chief Development Officer | 2025-10-31 | Option Exercise | 70,929 | 58.84 | 4,173,213 | 2025-11-03 20:14:45 |
| IONS | IONIS PHARMACEUTICALS INC | Swayze Eric | EVP Research | 2025-10-15 | Sell | 53 | 73.62 | 3,902 | 2025-10-16 20:16:46 |
| IONS | IONIS PHARMACEUTICALS INC | Swayze Eric | EVP Research | 2025-10-15 | Option Exercise | 125 | 0.00 | 0 | 2025-10-16 20:16:46 |
| IONS | IONIS PHARMACEUTICALS INC | PARSHALL B LYNNE | Directior | 2025-10-15 | Sell | 5,000 | 71.74 | 358,722 | 2025-10-16 20:16:14 |
| IONS | IONIS PHARMACEUTICALS INC | Devers Shannon L. | EVP, Chief Human Resources Ofc | 2025-10-15 | Sell | 7,263 | 73.06 | 530,638 | 2025-10-16 20:16:08 |
| IONS | IONIS PHARMACEUTICALS INC | Devers Shannon L. | EVP, Chief Human Resources Ofc | 2025-10-15 | Option Exercise | 8,820 | 33.00 | 291,060 | 2025-10-16 20:16:08 |
| IONS | IONIS PHARMACEUTICALS INC | Birchler Brian | EVP, Corp and Development Ops | 2025-10-14 | Sell | 23,900 | 72.13 | 1,723,987 | 2025-10-16 20:15:51 |
| IONS | IONIS PHARMACEUTICALS INC | Birchler Brian | EVP, Corp and Development Ops | 2025-10-14 | Option Exercise | 23,900 | 53.77 | 1,285,103 | 2025-10-16 20:15:51 |
| IONS | IONIS PHARMACEUTICALS INC | Birchler Brian | EVP, Corp and Development Ops | 2025-10-14 | Sell | 23,900 | 72.13 | 1,723,987 | 2025-10-16 20:15:51 |
| IONS | IONIS PHARMACEUTICALS INC | Birchler Brian | EVP, Corp and Development Ops | 2025-10-14 | Option Exercise | 23,900 | 53.77 | 1,285,103 | 2025-10-16 20:15:51 |
| IONS | IONIS PHARMACEUTICALS INC | Swayze Eric | EVP Research | 2025-10-06 | Sell | 6,849 | 69.02 | 472,718 | 2025-10-08 18:37:06 |
| IONS | IONIS PHARMACEUTICALS INC | Swayze Eric | EVP Research | 2025-10-06 | Sell | 6,849 | 69.02 | 472,718 | 2025-10-08 18:37:06 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2025-10-06 | Sell | 13,441 | 69.74 | 937,338 | 2025-10-08 18:37:00 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2025-10-06 | Option Exercise | 10,200 | 52.87 | 539,274 | 2025-10-08 18:37:00 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2025-10-06 | Sell | 13,441 | 69.74 | 937,338 | 2025-10-08 18:37:00 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2025-10-06 | Option Exercise | 10,200 | 52.87 | 539,274 | 2025-10-08 18:37:00 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2025-10-06 | Sell | 437 | 69.26 | 30,268 | 2025-10-08 18:36:54 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2025-10-06 | Sell | 437 | 69.26 | 30,268 | 2025-10-08 18:36:54 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2025-10-06 | Sell | 1,625 | 69.37 | 112,725 | 2025-10-08 18:36:47 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2025-10-06 | Sell | 1,625 | 69.37 | 112,725 | 2025-10-08 18:36:47 |
| IONS | IONIS PHARMACEUTICALS INC | WENDER JOSEPH H | Directior | 2025-10-01 | Sell | 16,800 | 65.50 | 1,100,385 | 2025-10-02 19:36:16 |
| IONS | IONIS PHARMACEUTICALS INC | Swayze Eric | EVP Research | 2025-10-01 | Sell | 27,114 | 66.16 | 1,793,744 | 2025-10-02 19:36:11 |
| IONS | IONIS PHARMACEUTICALS INC | Swayze Eric | EVP Research | 2025-10-01 | Option Exercise | 27,114 | 53.77 | 1,457,920 | 2025-10-02 19:36:11 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2025-10-02 | Sell | 64,664 | 67.69 | 4,377,055 | 2025-10-02 19:35:57 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2025-10-02 | Option Exercise | 64,664 | 58.97 | 3,813,257 | 2025-10-02 19:35:57 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2025-10-02 | Sell | 15,000 | 68.01 | 1,020,210 | 2025-10-02 19:35:51 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2025-10-02 | Option Exercise | 15,000 | 31.80 | 477,000 | 2025-10-02 19:35:51 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2025-09-29 | Sell | 25,300 | 64.62 | 1,634,922 | 2025-10-01 16:55:36 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2025-09-29 | Option Exercise | 25,300 | 56.78 | 1,436,534 | 2025-10-01 16:55:36 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2025-09-29 | Sell | 25,300 | 64.62 | 1,634,922 | 2025-10-01 16:55:36 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2025-09-29 | Option Exercise | 25,300 | 56.78 | 1,436,534 | 2025-10-01 16:55:36 |
| IONS | IONIS PHARMACEUTICALS INC | Geary Richard S | EVP, Chief Development Officer | 2025-09-30 | Sell | 57,900 | 65.24 | 3,777,668 | 2025-10-01 16:55:29 |
| IONS | IONIS PHARMACEUTICALS INC | Geary Richard S | EVP, Chief Development Officer | 2025-09-30 | Option Exercise | 57,900 | 53.77 | 3,113,283 | 2025-10-01 16:55:29 |
| IONS | IONIS PHARMACEUTICALS INC | Geary Richard S | EVP, Chief Development Officer | 2025-09-30 | Sell | 57,900 | 65.24 | 3,777,668 | 2025-10-01 16:55:29 |
| IONS | IONIS PHARMACEUTICALS INC | Geary Richard S | EVP, Chief Development Officer | 2025-09-30 | Option Exercise | 57,900 | 53.77 | 3,113,283 | 2025-10-01 16:55:29 |
| IONS | IONIS PHARMACEUTICALS INC | HOUGEN ELIZABETH L | EVP, Finance & CFO | 2025-09-30 | Sell | 49,800 | 65.26 | 3,249,734 | 2025-10-01 16:55:20 |
| IONS | IONIS PHARMACEUTICALS INC | HOUGEN ELIZABETH L | EVP, Finance & CFO | 2025-09-30 | Option Exercise | 49,800 | 53.77 | 2,677,746 | 2025-10-01 16:55:20 |
| IONS | IONIS PHARMACEUTICALS INC | HOUGEN ELIZABETH L | EVP, Finance & CFO | 2025-09-30 | Sell | 49,800 | 65.26 | 3,249,734 | 2025-10-01 16:55:20 |
| IONS | IONIS PHARMACEUTICALS INC | HOUGEN ELIZABETH L | EVP, Finance & CFO | 2025-09-30 | Option Exercise | 49,800 | 53.77 | 2,677,746 | 2025-10-01 16:55:20 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2025-09-12 | Sell | 1,700 | 64.58 | 109,787 | 2025-09-16 16:56:38 |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | 2025-09-12 | Option Exercise | 1,700 | 56.78 | 96,526 | 2025-09-16 16:56:38 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2025-09-09 | Sell | 11,950 | 62.16 | 742,838 | 2025-09-11 17:05:07 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2025-09-09 | Option Exercise | 11,950 | 31.80 | 380,010 | 2025-09-11 17:05:07 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2025-09-05 | Sell | 250 | 62.00 | 15,500 | 2025-09-09 18:30:41 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2025-09-05 | Option Exercise | 250 | 31.80 | 7,950 | 2025-09-09 18:30:41 |
| IONS | IONIS PHARMACEUTICALS INC | BENNETT C FRANK | EVP, Chief Scientific Officer | 2025-09-05 | Sell | 6,000 | 59.60 | 357,581 | 2025-09-09 18:30:25 |
| IONS | IONIS PHARMACEUTICALS INC | WENDER JOSEPH H | Directior | 2025-09-02 | Sell | 28,000 | 57.58 | 1,612,156 | 2025-09-04 20:40:10 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2025-09-03 | Sell | 203,814 | 60.32 | 12,294,703 | 2025-09-04 20:38:20 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2025-09-03 | Option Exercise | 203,814 | 44.32 | 9,032,039 | 2025-09-04 20:38:20 |
| IONS | IONIS PHARMACEUTICALS INC | Devers Shannon L. | EVP, Chief Human Resources Ofc | 2025-09-03 | Sell | 3,162 | 61.02 | 192,943 | 2025-09-04 20:36:34 |
| IONS | IONIS PHARMACEUTICALS INC | Devers Shannon L. | EVP, Chief Human Resources Ofc | 2025-09-03 | Option Exercise | 3,162 | 36.12 | 114,207 | 2025-09-04 20:36:34 |
| IONS | IONIS PHARMACEUTICALS INC | WENDER JOSEPH H | Directior | 2025-09-02 | Sell | 28,000 | 57.58 | 1,612,156 | 2025-09-04 20:34:45 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2025-09-03 | Sell | 32,800 | 59.34 | 1,946,220 | 2025-09-04 20:34:11 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2025-09-03 | Option Exercise | 32,800 | 31.80 | 1,043,040 | 2025-09-04 20:34:11 |
| IONS | IONIS PHARMACEUTICALS INC | Diaz Allene M. | Directior | 2025-08-22 | Sell | 1,427 | 42.53 | 60,687 | 2025-08-26 17:23:52 |
| IONS | IONIS PHARMACEUTICALS INC | BENNETT C FRANK | EVP, Chief Scientific Officer | 2025-08-18 | Sell | 10,000 | 43.98 | 439,776 | 2025-08-20 18:14:40 |
| IONS | IONIS PHARMACEUTICALS INC | BENNETT C FRANK | EVP, Chief Scientific Officer | 2025-08-18 | Option Exercise | 10,000 | 32.60 | 326,000 | 2025-08-20 18:14:40 |
| IONS | IONIS PHARMACEUTICALS INC | PARSHALL B LYNNE | Directior | 2025-08-06 | Sell | 5,000 | 41.93 | 209,646 | 2025-08-08 18:55:59 |
| IONS | IONIS PHARMACEUTICALS INC | Geary Richard S | EVP, Chief Development Officer | 2025-08-05 | Sell | 10,000 | 42.86 | 428,593 | 2025-08-06 18:44:16 |
| IONS | IONIS PHARMACEUTICALS INC | Schneider Eugene | EVP, Chf Clinical Develop Ofcr | 2025-08-04 | Sell | 9,549 | 42.80 | 408,701 | 2025-08-05 17:28:00 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2025-07-30 | Sell | 2,432 | 45.00 | 109,440 | 2025-08-01 16:06:41 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2025-07-30 | Option Exercise | 2,432 | 32.60 | 79,283 | 2025-08-01 16:06:41 |
| IONS | IONIS PHARMACEUTICALS INC | LOSCALZO JOSEPH | Directior | 2025-07-15 | Option Exercise | 4,079 | 0.00 | 0 | 2025-07-17 16:59:28 |
| IONS | IONIS PHARMACEUTICALS INC | YANG MICHAEL J. | Directior | 2025-07-15 | Option Exercise | 4,079 | 0.00 | 0 | 2025-07-17 16:54:38 |
| IONS | IONIS PHARMACEUTICALS INC | WENDER JOSEPH H | Directior | 2025-07-15 | Option Exercise | 4,079 | 0.00 | 0 | 2025-07-17 16:54:31 |
| IONS | IONIS PHARMACEUTICALS INC | PARSHALL B LYNNE | Directior | 2025-07-15 | Option Exercise | 4,079 | 0.00 | 0 | 2025-07-17 16:54:25 |
| IONS | IONIS PHARMACEUTICALS INC | HERMAN JOAN E | Directior | 2025-07-15 | Option Exercise | 4,079 | 0.00 | 0 | 2025-07-17 16:54:08 |
| IONS | IONIS PHARMACEUTICALS INC | Hayden Michael R | Directior | 2025-07-15 | Option Exercise | 4,079 | 0.00 | 0 | 2025-07-17 16:54:01 |
| IONS | IONIS PHARMACEUTICALS INC | Diaz Allene M. | Directior | 2025-07-15 | Option Exercise | 4,079 | 0.00 | 0 | 2025-07-17 16:53:54 |
| IONS | IONIS PHARMACEUTICALS INC | BERTHELSEN SPENCER R | Directior | 2025-07-15 | Option Exercise | 4,079 | 0.00 | 0 | 2025-07-17 16:53:48 |
| IONS | IONIS PHARMACEUTICALS INC | Monia Brett P | Chief Executive Officer | 2025-07-11 | Sell | 1,160 | 41.74 | 48,416 | 2025-07-15 20:54:09 |
| IONS | IONIS PHARMACEUTICALS INC | Hayden Michael R | Directior | 2025-05-01 | Buy | 15,000 | 31.86 | 477,900 | 2025-05-02 16:38:26 |
| IONS | IONIS PHARMACEUTICALS INC | Birchler Brian | EVP, Corp and Development Ops | 2025-04-15 | Sell | 680 | 28.37 | 19,292 | 2025-04-17 16:53:27 |
| IONS | IONIS PHARMACEUTICALS INC | Birchler Brian | EVP, Corp and Development Ops | 2025-04-15 | Option Exercise | 1,875 | 0.00 | 0 | 2025-04-17 16:53:27 |
| IONS | IONIS PHARMACEUTICALS INC | Jenne Kyle | EVP, Chf GL Pdt Str Ofcr | 2025-04-15 | Sell | 3,016 | 28.36 | 85,534 | 2025-04-17 16:53:18 |
| IONS | IONIS PHARMACEUTICALS INC | Jenne Kyle | EVP, Chf GL Pdt Str Ofcr | 2025-04-15 | Option Exercise | 12,226 | 0.00 | 0 | 2025-04-17 16:53:18 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2025-04-15 | Sell | 3,928 | 28.40 | 111,555 | 2025-04-17 16:53:11 |
| IONS | IONIS PHARMACEUTICALS INC | Baroldi Joseph | EVP, Chief Business Officer | 2025-04-15 | Option Exercise | 10,837 | 0.00 | 0 | 2025-04-17 16:53:11 |
